Periodontal inflammation and systemic diseases: an overview

M Martínez-García, E Hernández-Lemus - Frontiers in physiology, 2021 - frontiersin.org
Periodontitis is a common inflammatory disease of infectious origins that often evolves into a
chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis …

Periodontal ligament stem cells: regenerative potency in periodontium

A Tomokiyo, N Wada, H Maeda - Stem cells and development, 2019 - liebertpub.com
Periodontium is consisted of root cementum, bone lining the tooth socket, gingiva facing the
tooth, and periodontal ligament (PDL). Its primary functions are support of the tooth and …

[HTML][HTML] Chitosan hydrogel incorporated with dental pulp stem cell-derived exosomes alleviates periodontitis in mice via a macrophage-dependent mechanism

Z Shen, S Kuang, Y Zhang, M Yang, W Qin, X Shi… - Bioactive materials, 2020 - Elsevier
Periodontitis is caused by host immune-inflammatory response to bacterial insult. A high
proportion of pro-inflammatory macrophages to anti-inflammatory macrophages leads to the …

A novel injectable piezoelectric hydrogel for periodontal disease treatment

L Roldan, C Montoya, V Solanki, KQ Cai… - … Applied Materials & …, 2023 - ACS Publications
Periodontal disease is a multifactorial, bacterially induced inflammatory condition
characterized by the progressive destruction of periodontal tissues. The successful …

Periodontal bone-ligament-cementum regeneration via scaffolds and stem cells

J Liu, J Ruan, MD Weir, K Ren, A Schneider, P Wang… - Cells, 2019 - mdpi.com
Periodontitis is a prevalent infectious disease worldwide, causing the damage of periodontal
support tissues, which can eventually lead to tooth loss. The goal of periodontal treatment is …

Concise review: periodontal tissue regeneration using stem cells: strategies and translational considerations

XY Xu, X Li, J Wang, XT He, HH Sun… - Stem cells translational …, 2019 - academic.oup.com
Periodontitis is a widespread disease characterized by inflammation-induced progressive
damage to the tooth-supporting structures until tooth loss occurs. The regeneration of …

Molecular basis beyond interrelated bone resorption/regeneration in periodontal diseases: a concise review

KM Sadek, S El Moshy, IA Radwan, D Rady… - International Journal of …, 2023 - mdpi.com
Periodontitis is the sixth most common chronic inflammatory disease, destroying the tissues
supporting the teeth. There are three distinct stages in periodontitis: infection, inflammation …

An in vitro comparative study of multisource derived human mesenchymal stem cells for bone tissue engineering

Y Zhang, Y Xing, L Jia, Y Ji, B Zhao… - Stem cells and …, 2018 - liebertpub.com
Mesenchymal stem cells (MSCs) have been considered promising tools for tissue
engineering and regenerative medicine. However, the optimal cell source for bone …

Collagen-based biomaterials in periodontal regeneration: Current applications and future perspectives of plant-based collagen

T Binlateh, P Thammanichanon, P Rittipakorn… - Biomimetics, 2022 - mdpi.com
Collagen is the most widely distributed protein in human body. Within the field of tissue
engineering and regenerative medical applications, collagen-based biomaterials have been …

Role of gingival mesenchymal stem cell exosomes in macrophage polarization under inflammatory conditions

R Wang, Q Ji, C Meng, H Liu, C Fan, S Lipkind… - International …, 2020 - Elsevier
Objective Exosomes have been shown to play a strong role in intercellular communication.
While GMSCs have been extensively studied, less research exists on exosomes derived …