Glucocorticoids (GCs) are steroids secreted by the adrenal cortex under the hypothalamic-
pituitary-adrenal axis control, one of the major neuro-endocrine systems of the organism …

Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

Epicardial adipose tissue (EAT) is part of the visceral adipose tissue (VAT) that surrounds
the heart and it is a quantifiable, modifiable, and multifaceted tissue that has both local and …

Epicardial adipose tissue is an unusual visceral fat depot with anatomical and functional
contiguity to the myocardium and coronary arteries. Under physiological conditions …

The primary adrenal cortical steroid hormones, aldosterone, and the glucocorticoids cortisol
and corticosterone, act through the structurally similar mineralocorticoid (MR) and …

Obesity (especially visceral adiposity) can be associated with 3 different phenotypes of heart
failure: heart failure with a reduced ejection fraction, heart failure with a preserved ejection …

Central obesity is associated with insulin resistance and dyslipidemia. Thus, the
mechanisms that control fat distribution and its impact on systemic metabolism have …

Adipocytes are the defining cell type of adipose tissue. Once considered a passive
participant in energy storage, adipose tissue is now recognized as a dynamic organ that …

We reported aldosterone as a novel adipocyte-derived factor that regulates vascular
function. We aimed to investigate molecular mechanisms, signaling pathways, and …

There has been a recent increase in our understanding in the isolation, culture, and
differentiation of mesenchymal stem cells (MSCs). Concomitantly, the availability of MSCs …