Sigma factors are multi-domain subunits of bacterial RNA polymerase (RNAP) that play
critical roles in transcription initiation, including the recognition and opening of promoters as …

Membrane-spanning signaling pathways enable bacteria to alter gene expression in
response to extracytoplasmic stimuli. Many such pathways are cell-surface signaling (CSS) …

During active growth of Escherichia coli, majority of the transcriptional activity is carried out
by the housekeeping sigma factor (σ70), whose association with core RNAP is generally …

A vast range of extracellular polysaccharides are produced by bacteria in order to adapt to
and thrive in diverse environmental niches. Many of these polymers have attracted great …

In bacteria, σ factors are essential for the promoter DNA-binding specificity of RNA
polymerase. The σ factors themselves are regulated by anti-σ factors that bind and inhibit …

Pseudomonas aeruginosa is a re-emerging, multidrug-resistant, opportunistic pathogen that
threatens the lives of immunocompromised patients, patients with cystic fibrosis, and those …

Transporters belonging to the r esistance-n odulation-d ivision (RND) superfamily of proteins
are invariably present in the genomes of Gram-negative bacteria and are largely …

In the Gram‐negative pathogen Pseudomonas aeruginosa, the alternative sigma factor
PvdS acts as a key regulator of the response to iron starvation. PvdS also controls P …

Iron is essential for most life forms. Under iron-limiting conditions, many bacteria produce
and release siderophores—molecules with high affinity for iron—which are then transported …

The Escherichia coli Rsd protein binds tightly and specifically to the RNA polymerase
(RNAP) σ70 factor. Rsd plays a role in alternative σ factor-dependent transcription by …