G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the
physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from …

Psychotropic drugs acting on monoamine neurotransmission are major pharmacological
treatments for neuropsychiatric conditions such as schizophrenia, depression, bipolar …

Background Accumulating evidence suggests that commensal bacteria consumption has the
potential to have a positive impact on stress‐related psychiatric disorders. However, the …

The tail-suspension test is a mouse behavioral test useful in the screening of potential
antidepressant drugs, and assessing of other manipulations that are expected to affect …

Prenatal stress is associated with an increased vulnerability to neurodevelopmental
disorders, including autism and schizophrenia. To determine the critical time window when …

Autism is a behaviorally defined neurodevelopmental disorder of unknown etiology. Mouse
models with face validity to the core symptoms offer an experimental approach to test …

The antidepressant action of cannabis as well as the interaction between antidepressants
and the endocannabinoid system has been reported. This study was conducted to assess …

Abstract Rationale Serotonin reuptake inhibitors (SSRIs) are effective in treating depression.
Given the existence of different families and subtypes of 5-HT receptors, multiple 5-HT …

Dysregulation of brain serotonin (5-HT) neurotransmission is thought to underlie mental
conditions as diverse as depression, anxiety disorders, bipolar disorder, autism, and …

Animal studies over the past two decades have led to extensive advances in our
understanding of pathogenesis of depressive and mood disorders. Among these, rodent …