Substance use disorders occur commonly in patients with schizophrenia and dramatically
worsen their overall clinical course. While the exact mechanisms contributing to substance …

In the present review, an integrated approach to craving and addiction is discussed, which is
based on recent insights from psychology and neuropsychopharmacology. An integrated …

Retrospective studies in humans suggest that chronic maternal stress during pregnancy,
associated with raised plasma levels of CRH, ACTH and cortisol may increase the likelihood …

It is commonly held that substance use comorbidity in schizophrenia represents self-
medication, an attempt by patients to alleviate adverse positive and negative symptoms …

Prenatal exposure to infection is associated with increased liability to schizophrenia, and it is
believed that such an association is mediated by the maternal immune response, in …

The authors test a neurocomputational model of dopamine function in cognition by
administering to healthy participants low doses of D₂ agents cabergoline and haloperidol …

Epidemiological studies have indicated an association between maternal bacterial and viral
infections during pregnancy and the higher incidence of schizophrenia in the resultant …

Psychiatry is the branch of medicine that addresses disorders of behavior and the
psychological processes that underlie behavior. Much of what it deals with consists in …

Creativity is considered a positive personal trait. However, highly creative people have
demonstrated elevated risk for certain forms of psychopathology, including mood disorders …

The prefrontal cortex (PFC) has long been known to be involved in the mediation of complex
behavioral responses. Considerable research efforts are directed towards refining the …