[HTML][HTML] Advances in the integration of metabolomics and metagenomics for human gut microbiome and their clinical applications
F Puig-Castellví, R Pacheco-Tapia, M Deslande… - TrAC Trends in …, 2023 - Elsevier
The human microbiome and its metabolic output play an important role in shaping human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …
health and disease. The host-microbe crosstalk is often characterised using metabolomics …
[HTML][HTML] Metabolomics-based development of bioproduction processes toward industrial-scale production
Highlights•Metabolomics accelerates bioproduction via strain, culture, and model
improvement.•Metabolomics is a powerful driving force for the DBTL-based strain …
improvement.•Metabolomics is a powerful driving force for the DBTL-based strain …
Engineering Escherichia coli for robustly producing succinic acid and 1, 4-butanediol together
Z Zhang, LH Liu, M Yang, H Cui, Q He, X Zheng… - Sustainable Materials …, 2025 - Elsevier
Abstract Biosynthetic succinic acid and 1, 4-butanediol (1, 4-BDO) are attractive due to their
high quality, low cost, and environmental sustainability, yet their yields are limited by weak …
high quality, low cost, and environmental sustainability, yet their yields are limited by weak …
Molecular basis for detection of sweet taste perception of mannitol depending on pH condition
S Eom, M Pyeon, M Moon, HD Yeom, JH Song… - Food Bioscience, 2024 - Elsevier
Mannitol is a sugar alcohol component naturally present in various kinds of seaweed and
fruits. During the late stages of kimchi fermentation, considerable quantity of mannitol is …
fruits. During the late stages of kimchi fermentation, considerable quantity of mannitol is …
Effect of adaptive laboratory evolution of engineered Escherichia coli in acetate on the biosynthesis of succinic acid from glucose in two-stage cultivation
J Jiang, Y Luo, P Fei, Z Zhu, J Peng, J Lu, D Zhu… - Bioresources and …, 2024 - Springer
Abstract Escherichia coli MLB (MG1655 Δ pflB Δ ldhA), which can hardly grow on glucose
with little succinate accumulation under anaerobic conditions. Two-stage fermentation is a …
with little succinate accumulation under anaerobic conditions. Two-stage fermentation is a …
Metabolomics of Escherichia coli for Disclosing Novel Metabolic Engineering Strategies for Enhancing Hydrogen and Ethanol Production
A Valle, ME de la Calle, H Muhamadali… - International Journal of …, 2023 - mdpi.com
The biological production of hydrogen is an appealing approach to mitigating the
environmental problems caused by the diminishing supply of fossil fuels and the need for …
environmental problems caused by the diminishing supply of fossil fuels and the need for …
Metabolic rewiring of microbial cell factories for improved production of succinic acid
Succinic acid (SA) is a valuable platform chemical with diverse applications. It serves as a
precursor for synthesizing tetrahydrofuran, γ-butyrolactone, 1, 4-butanediol, and …
precursor for synthesizing tetrahydrofuran, γ-butyrolactone, 1, 4-butanediol, and …
Microbial Metabolomics: An Overview of Applications
PMM van der Velden, RS Jansen - Metabolomics: Recent Advances and …, 2023 - Springer
Microorganisms are the most abundant form of life and thrive in almost any habitat on Earth.
Despite their size, they can cause severe illness, clean contaminated soils and water, and …
Despite their size, they can cause severe illness, clean contaminated soils and water, and …
Bioreactor Technology for Succinic and Fumaric Acids
D Mousdale - Bioreactor Technology in Food Processing - taylorfrancis.com
Succinic and fumaric are C4 dicarboxylic acids, which are adjacent intermediates of the
tricarboxylic acid cycle related reversibly by the action of succinate dehydrogenase. Both …
tricarboxylic acid cycle related reversibly by the action of succinate dehydrogenase. Both …