Relapse of acute myeloid leukemia after allogeneic stem cell transplantation: immune escape mechanisms and current implications for therapy
T Sauerer, GF Velázquez, C Schmid - Molecular Cancer, 2023 - Springer
Acute myeloid leukemia (AML) is a heterogeneous disease characterized by the expansion
of immature myeloid cells in the bone marrow (BM) and peripheral blood (PB) resulting in …
of immature myeloid cells in the bone marrow (BM) and peripheral blood (PB) resulting in …
[PDF][PDF] 急性髓系白血病造血干细胞移植后复发的预防及治疗
仲照东， 陈智超， 夏凌辉 - 临床血液学杂志, 2022 - whuhzzs.com
异基因造血干细胞移植是目前治愈急性髓系白血病(acutemyeloidleukemia, AML) 的唯一方法,
但超过30% 的AML 患者存在移植后复发. 复发患者预后不佳, 2 年的总生存(OS) 率不足15 …
但超过30% 的AML 患者存在移植后复发. 复发患者预后不佳, 2 年的总生存(OS) 率不足15 …
Hypomethylating agent-based therapies in older adults with acute myeloid leukemia–A joint review by the Young International Society of Geriatric Oncology and …
NR Neuendorff, N Gagelmann, S Singhal… - Journal of geriatric …, 2023 - Elsevier
Acute myeloid leukemia (AML) is associated with poor outcomes in older adults. A major
goal of treatment is to balance quality of life and functional independence with disease …
goal of treatment is to balance quality of life and functional independence with disease …
Higher cyclosporine-A concentration increases the risk of relapse in AML following allogeneic stem cell transplantation from unrelated donors using anti-thymocyte …
M Lisak, M Nicklasson, R Palmason, S Wichert… - Scientific Reports, 2023 - nature.com
Cyclosporine-A (CsA) is used to prevent acute graft-versus-host disease (aGvHD).
European Society for Blood and Marrow transplantation (EBMT) recommends a CsA target …
European Society for Blood and Marrow transplantation (EBMT) recommends a CsA target …
Targeting IDH2R140Q and other neoantigens in acute myeloid leukemia
For patients with high-risk or relapsed/refractory acute myeloid leukemia (AML), allogeneic
stem cell transplantation (allo-HSCT) and the graft-versus-leukemia effect mediated by …
stem cell transplantation (allo-HSCT) and the graft-versus-leukemia effect mediated by …
Improvements in Posttransplant Outcomes Over Two Decades in Older Patients with Acute Myeloid Leukemia in the EBMT ALWP Study
Purpose: Acute myeloid leukemia (AML) is a disease of older patients. Progress in
allogeneic hematopoietic cell transplantation (allo-HCT) allowed the delivery of allo-HCT to …
allogeneic hematopoietic cell transplantation (allo-HCT) allowed the delivery of allo-HCT to …
Navigating preemptive and therapeutic donor lymphocyte infusions in advanced myeloid malignancies by high-sensitivity chimerism analysis
M Stadler, L Venturini, I Bünting, E Dammann… - Frontiers in …, 2022 - frontiersin.org
Preemptive and therapeutic donor lymphocyte infusions (preDLI and tDLI) are widely used
in relapsing and relapsed hematopoietic malignancies after allogeneic stem cell …
in relapsing and relapsed hematopoietic malignancies after allogeneic stem cell …
Venetoclax plus hypomethylating agents versus intensive chemotherapy for hematological relapse of myeloid malignancies after allo-HSCT
Z Chen, S Zhen, T Zhang, Y Shen, A Pang… - Frontiers in …, 2023 - frontiersin.org
Introduction Since allogeneic stem cell transplantation (allo-HSCT) is considered one of the
curative treatments for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) …
curative treatments for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) …
Metabolic instruction of the graft-versus-leukemia immunity
AC Burk, P Apostolova - Frontiers in immunology, 2024 - frontiersin.org
Allogeneic hematopoietic cell transplantation (allo-HCT) is frequently performed to cure
hematological malignancies, such as acute myeloid leukemia (AML), through the graft …
hematological malignancies, such as acute myeloid leukemia (AML), through the graft …
Transgenic HA-1-Specific CD8+ T-Lymphocytes Selectively Target Leukemic Cells
A Pilunov, DS Romaniuk, A Shmelev, S Sheetikov… - Cancers, 2023 - mdpi.com
Simple Summary A relapse of the malignant disease frequently occurs after allogeneic
hematopoietic stem cell transplantation. Immune recognition of minor histocompatibility …
hematopoietic stem cell transplantation. Immune recognition of minor histocompatibility …