Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa
isolates are frequent causes of serious nosocomial infections that may compromise the …
isolates are frequent causes of serious nosocomial infections that may compromise the …
Phage therapy in the postantibiotic era
FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …
number of infections are becoming harder or almost impossible to treat, carrying high …
Protein cages: from fundamentals to advanced applications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …
Expansion of bacteriophages is linked to aggravated intestinal inflammation and colitis
Bacteriophages are the most abundant members of the microbiota and have the potential to
shape gut bacterial communities. Changes to bacteriophage composition are associated …
shape gut bacterial communities. Changes to bacteriophage composition are associated …
Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double …
Background Wound infections are the main cause of sepsis in patients with burns and
increase burn-related morbidity and mortality. Bacteriophages, natural bacterial viruses, are …
increase burn-related morbidity and mortality. Bacteriophages, natural bacterial viruses, are …
Intravesical bacteriophages for treating urinary tract infections in patients undergoing transurethral resection of the prostate: a randomised, placebo-controlled, double …
Summary Background Urinary tract infections (UTIs) are among the most prevalent microbial
diseases and their financial burden on society is substantial. In the context of increasing …
diseases and their financial burden on society is substantial. In the context of increasing …
Translating phage therapy into the clinic: Recent accomplishments but continuing challenges
A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …
Bacteriophage therapy: clinical trials and regulatory hurdles
LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …
development have fuelled innovation in other research fields and led to a revitalization of …
[HTML][HTML] Engineering phage host-range and suppressing bacterial resistance through phage tail fiber mutagenesis
The rapid emergence of antibiotic-resistant infections is prompting increased interest in
phage-based antimicrobials. However, acquisition of resistance by bacteria is a major issue …
phage-based antimicrobials. However, acquisition of resistance by bacteria is a major issue …
[HTML][HTML] Biotechnological applications of bacteriophages: State of the art
Bacteriophage particles are the most abundant biological entities on our planet, infecting
specific bacterial hosts in every known environment and being major drivers of bacterial …
specific bacterial hosts in every known environment and being major drivers of bacterial …