For the last few decades, Calcineurin inhibitors (CNI)-based therapy has been the pillar of
immunosuppression for prevention of organ transplant rejection. However, despite exerting …

Belatacept is the first costimulatory blockade agent clinically approved for transplant
immunosuppression. While more than ten years of study have demonstrated that belatacept …

Belatacept may be an alternative to calcineurin inhibitors and may contribute to improved
long term metabolic and allograft outcomes in kidney transplant recipients. Careful selection …

The first liver transplant, performed by Dr Thomas Starzl in 1967, used a combination of
azathioprine, steroids, and heterolygous antilymphocyte globulin (ALG) for …

Calcineurin inhibitors (CNIs) are essential in liver transplantation (LT); however, their long-
term use leads to various adverse effects. The anti–intercellular adhesion molecule (ICAM) …

While effective immunosuppressant (IS) medications have radically improved survival in
solid organ transplantation (SOT), they are also a major cause of neurologic complications …