Adenovirus pneumonia is common in pediatric upper respiratory tract infection, which is
comparatively easy to develop into severe cases and has a high mortality rate with many …

Skin, the largest human organ, is part of the first line of physical and immunological defense
against many pathogens. Understanding how skin antigen‐presenting cells (APCs) respond …

Nuclear mRNA metabolism is regulated by multiple proteins, which either directly bind to
RNA or form multiprotein complexes. The RNA-binding protein ZC3H11A is involved in …

Carcinomas are characterized by a widespread upregulation of intercellular junctions that
create a barrier to immune response and drug therapy. Desmoglein 2 (DSG2) represents …

Background Adenoviral vectors are among the most frequently used vectors for gene
therapy and cancer treatment. Most vectors are derived from human adenovirus (Ad) …

The adenoviral vector based AstraZeneca and Janssen COVID vaccines have been
associated with rare cases of thrombosis, a condition which depends on adenovirus binding …

Pathogenic adenovirus (Ad) infections are widespread but typically mild and transient,
except in the immunocompromised. As vectors for gene therapy, vaccine, and oncology …

Certain species D human adenoviruses (HAdV-D19,-D37, and-D64) are causative agents of
epidemic keratoconjunctivitis. HAdV-D37 has previously been shown to bind CD46 …

Background The therapeutic potential of oncolytic measles virotherapy has been
demonstrated across various malignancies. However, the effectiveness against human …

More than 100 human adenovirus (Ad) types were identified, of which species D comprises
the largest group. Heparan sulfate proteoglycans (HSPGs) were shown to function as cell …