Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002)
SR Cairns, JH Scholefield, RJ Steele, MG Dunlop… - Gut, 2010 - gut.bmj.com
The British Society of Gastroenterology (BSG) and the Association of Coloproctology for
Great Britain and Ireland (ACPGBI) commissioned this update of the 2002 guidance. The …
Great Britain and Ireland (ACPGBI) commissioned this update of the 2002 guidance. The …
Risk of prostate cancer in Lynch syndrome: a systematic review and meta-analysis
S Ryan, MA Jenkins, AK Win - Cancer epidemiology, biomarkers & …, 2014 - AACR
It has been controversial that men carrying a DNA mismatch repair (MMR) gene mutation
(Lynch syndrome) are at heightened risk of prostate cancer given that an increased risk is …
(Lynch syndrome) are at heightened risk of prostate cancer given that an increased risk is …
Prevalence and penetrance of major genes and polygenes for colorectal cancer
Background: Although high-risk mutations in identified major susceptibility genes (DNA
mismatch repair genes and MUTYH) account for some familial aggregation of colorectal …
mismatch repair genes and MUTYH) account for some familial aggregation of colorectal …
Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study
Purpose To determine whether cancer risks for carriers and noncarriers from families with a
mismatch repair (MMR) gene mutation are increased above the risks of the general …
mismatch repair (MMR) gene mutation are increased above the risks of the general …
Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery
S Parry, AK Win, B Parry, FA Macrae, LC Gurrin… - Gut, 2011 - gut.bmj.com
Background Surgical management of colon cancer for patients with Lynch syndrome who
carry a mismatch repair (MMR) gene mutation is controversial. The decision to remove more …
carry a mismatch repair (MMR) gene mutation is controversial. The decision to remove more …
Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer
RA Barnetson, A Tenesa, SM Farrington… - New England journal …, 2006 - Mass Medical Soc
Background The identification of mutations in germ-line DNA mismatch-repair genes at the
time of diagnosis of colorectal cancer is important in the management of the disease …
time of diagnosis of colorectal cancer is important in the management of the disease …
Heterozygous BRCA1 and BRCA2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer
Background Genetic predisposition is has been identified as a cause of cancer, yet little is
known about the role of adult cancer predisposition syndromes in childhood cancer. We …
known about the role of adult cancer predisposition syndromes in childhood cancer. We …
Risk of colorectal and endometrial cancer for carriers of mutations of the hMLH1 and hMSH2 gene: correction for ascertainment
F Quehenberger, HFA Vasen… - Journal of medical …, 2005 - jmg.bmj.com
Background: Hereditary non-polyposis colorectal cancer (HNPCC) is caused by germline
mutations of mismatch repair genes, usually in hMLH1 or hMSH2. All earlier studies on …
mutations of mismatch repair genes, usually in hMLH1 or hMSH2. All earlier studies on …
Guidance on gastrointestinal surveillance for hereditary non-polyposis colorectal cancer, familial adenomatous polypolis, juvenile polyposis, and Peutz-Jeghers …
MG Dunlop - Gut, 2002 - gut.bmj.com
People with a greatly increased risk of gastrointestinal malignancy on the basis of
inheritance of a single gene disorder can be identified on the basis of family history and …
inheritance of a single gene disorder can be identified on the basis of family history and …
Risk of breast cancer in Lynch syndrome: a systematic review
Introduction Lynch syndrome is an autosomal dominantly inherited disorder of cancer
susceptibility caused by germline mutations in the DNA mismatch repair (MMR) genes …
susceptibility caused by germline mutations in the DNA mismatch repair (MMR) genes …