The knee meniscus: structure–function, pathophysiology, current repair techniques, and prospects for regeneration
Extensive scientific investigations in recent decades have established the anatomical,
biomechanical, and functional importance that the meniscus holds within the knee joint. As a …
biomechanical, and functional importance that the meniscus holds within the knee joint. As a …
Meniscus, articular cartilage and nucleus pulposus: a comparative review of cartilage-like tissues in anatomy, development and function
S Chen, P Fu, H Wu, M Pei - Cell and tissue research, 2017 - Springer
The degradation of cartilage in the human body is impacted by aging, disease, genetic
predisposition and continued insults resulting from daily activity. The burden of cartilage …
predisposition and continued insults resulting from daily activity. The burden of cartilage …
Cell migration: implications for repair and regeneration in joint disease
Connective tissues within the synovial joints are characterized by their dense extracellular
matrix and sparse cellularity. With injury or disease, however, tissues commonly experience …
matrix and sparse cellularity. With injury or disease, however, tissues commonly experience …
[HTML][HTML] Driving hierarchical collagen fiber formation for functional tendon, ligament, and meniscus replacement
Hierarchical collagen fibers are the primary source of strength in musculoskeletal tendons,
ligaments, and menisci. It has remained a challenge to develop these large fibers in …
ligaments, and menisci. It has remained a challenge to develop these large fibers in …
Tissue-specific parameters for the design of ECM-mimetic biomaterials
The extracellular matrix (ECM) is a complex network of biomolecules that mechanically and
biochemically directs cell behavior and is crucial for maintaining tissue function and health …
biochemically directs cell behavior and is crucial for maintaining tissue function and health …
Digital micromirror device projection printing system for meniscus tissue engineering
Meniscus degeneration due to age or injury can lead to osteoarthritis. Although promising,
current cell-based approaches show limited success. Here we present three-dimensional …
current cell-based approaches show limited success. Here we present three-dimensional …
The meniscus tear: a review of stem cell therapies
G Jacob, K Shimomura, AJ Krych, N Nakamura - Cells, 2019 - mdpi.com
Meniscal injuries have posed a challenging problem for many years, especially considering
that historically the meniscus was considered to be a structure with no important role in the …
that historically the meniscus was considered to be a structure with no important role in the …
Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair
A Chevrier, M Nelea, MB Hurtig… - Journal of …, 2009 - Wiley Online Library
Meniscus injury is a frequently encountered clinical orthopedic issue and is
epidemiologically correlated to osteoarthritis. The development of new treatments for …
epidemiologically correlated to osteoarthritis. The development of new treatments for …
Age-related changes in the knee meniscus
A Tsujii, N Nakamura, S Horibe - The Knee, 2017 - Elsevier
Background Aging is the most prominent risk factor for the development of osteoarthritis
(OA), which affects knees and causes major health burdens. Meniscal dysfunction mostly …
(OA), which affects knees and causes major health burdens. Meniscal dysfunction mostly …
Perlecan in pericellular mechanosensory cell-matrix communication, extracellular matrix stabilisation and mechanoregulation of load-bearing connective tissues
In this study, we review mechanoregulatory roles for perlecan in load-bearing connective
tissues. Perlecan facilitates the co-acervation of tropoelastin and assembly of elastic …
tissues. Perlecan facilitates the co-acervation of tropoelastin and assembly of elastic …