Adaptive laboratory evolution of ale and lager yeasts for improved brewing efficiency and beer quality

B Gibson, M Dahabieh, K Krogerus… - Annual review of …, 2020 - annualreviews.org
Yeasts directly impact the efficiency of brewery fermentations as well as the character of the
beers produced. In recent years, there has been renewed interest in yeast selection and …

The Model System Saccharomyces cerevisiae Versus Emerging Non-Model Yeasts for the Production of Biofuels

MP Lacerda, EJ Oh, C Eckert - Life, 2020 - mdpi.com
Microorganisms are effective platforms for the production of a variety of chemicals including
biofuels, commodity chemicals, polymers and other natural products. However, deep cellular …

Metabolic Plasticity of Candida albicans in Response to Different Environmental Conditions

M Gallo, L Giovati, W Magliani, TA Pertinhez, S Conti… - Journal of Fungi, 2022 - mdpi.com
The ubiquitous commensal Candida albicans, part of the human microbiota, is an
opportunistic pathogen able to cause a wide range of diseases, from cutaneous mycoses to …

Multimodal regularized linear models with flux balance analysis for mechanistic integration of omics data

G Magazzù, G Zampieri, C Angione - Bioinformatics, 2021 - academic.oup.com
Motivation High-throughput biological data, thanks to technological advances, have become
cheaper to collect, leading to the availability of vast amounts of omic data of different types …

A hybrid strategy for growth-associated production of sophorolipid using a reconstructed genome-scale metabolic model for the fructophilic yeast Starmerella …

E Motamedian, MR Baumanis, JE Daugavietis… - Process Safety and …, 2024 - Elsevier
Metabolic modeling of Starmerella bombicola as a model yeast of the Wickerhamiella/
Starmerella (W/S) clade is advantageous for studying the characteristics of this clade and to …

Evaluating accessibility, usability and interoperability of genome-scale metabolic models for diverse yeasts species

I Domenzain, F Li, EJ Kerkhoven… - FEMS Yeast …, 2021 - academic.oup.com
Metabolic network reconstructions have become an important tool for probing cellular
metabolism in the field of systems biology. They are used as tools for quantitative prediction …

Systematically gap-filling the genome-scale metabolic model of CHO cells

H Fouladiha, SA Marashi, S Li, Z Li, HO Masson… - Biotechnology …, 2021 - Springer
Objective Chinese hamster ovary (CHO) cells are the leading cell factories for producing
recombinant proteins in the biopharmaceutical industry. In this regard, constraint-based …

Multimodal microorganism development: integrating top-down biological engineering with bottom-up rational design

MS Dahabieh, JM Thevelein, B Gibson - Trends in biotechnology, 2020 - cell.com
Biological engineering has unprecedented potential to solve society's most pressing
challenges. Engineering approaches must consider complex technical, economic, and …

merlin v4.0: an updated platform for the reconstruction of high-quality genome-scale metabolic models

J Capela, D Lagoa, R Rodrigues, E Cunha, F Cruz… - bioRxiv, 2021 - biorxiv.org
Genome-scale metabolic models have been recognised as useful tools for better
understanding living organisms' metabolism. merlin (https://www. merlin-sysbio. org/) is an …

[HTML][HTML] Production of Amino Acids and Nucleic Acids from Genetically Engineered Microbial Cells and their Relevance to Biodegradation

AI Hassan, HM Saleh - Green Energy and Environmental …, 2023 - intechopen.com
The biodegradation of diverse organic compounds plays a pivotal role in environmental
sustainability and waste management. In recent years, genetically engineered microbial …