Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell
growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the …

Ribosomes are a complex ensemble of rRNA and ribosomal proteins that function as mRNA
translation machines. Ribosome biogenesis is a multistep process that begins in the …

Although ribosomal proteins are known for playing an essential role in ribosome assembly
and protein translation, their ribosome-independent functions have also been greatly …

With the development of radiotherapeutic oncology, computer technology and medical
imaging technology, radiation therapy has made great progress. Research on the impact …

The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and
ribosomal proteins (RPs). The latter have been shown to have many ribosomal and …

Ribosomes are essential components of the protein synthesis machinery. The process of
ribosome biogenesis is well organized and tightly regulated. Recent studies have shown …

Background Lung cancer has long been the most dangerous malignant tumor among males
in both well developed and poorly developed countries. Radiotherapy plays a critical role in …

Simple Summary Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) is an
intracellular adapter protein with E3 ligase activity, which interacts with a plethora of other …

Background Clear cell renal cell carcinoma (ccRCC) arises from the renal parenchymal
epithelium and is the predominant malignant entity of renal cancer, exhibiting increasing …

Ubiquitin-conjugating enzyme E2 J1 (UBE2J1) has been proven to participate in the
ubiquitination of multiple substrate proteins. However, the underlying mechanisms of …