Oligodendrocyte progenitor cells (OPCs) play pivotal roles in myelin formation and
phagocytosis, communicating with neighboring cells and contributing to the integrity of the …

Epilepsy is a neurological disorder caused by the pathological hyper-synchronization of
neuronal discharges. The fundamental research of epilepsy mechanisms and the targets of …

Glial cells are the most abundant and widely distributed cells that maintain cerebral
homeostasis in the central nervous system. They mainly include microglia, astrocytes, and …

The central nervous system (CNS) is home to neuronal and glial cells. Traditionally, glia was
disregarded as just the structural support across the brain and spinal cord, in striking …

Multiple system atrophy (MSA) is a debilitating movement disorder with unknown etiology.
Patients present characteristic parkinsonism and/or cerebellar dysfunction in the clinical …

Considerable evidence has shown that the breakdown of myelin has been linked to
Alzheimer's disease (AD). Considering the vulnerability of oligodendrocytes to Alzheimer's …

After the discovery of adult neurogenesis (stem cell-driven production of new neuronal
elements), it is conceivable to find young, undifferentiated neurons mixed with mature …

Preterm cerebral white matter injury (WMI), a major form of prenatal brain injury, may
potentially be treated by oligodendrocyte (OL) precursor cell (OPC) transplantation …

Oligodendrocyte precursor cells (OPCs) sculpt neural circuits through the phagocytic
engulfment of synapses during development and adulthood. However, existing techniques …

Efficient strategies for neuroprotection and repair are still an unmet medical need for
neurodegenerative diseases and lesions of the central nervous system. Over the last few …