Genome-wide association studies (GWAS) have provided insights into the genetic basis of
complex diseases. In the next step, integrative multi-omics approaches can characterize …

Suppressing inflammation has been the primary focus of therapies in autoimmune rheumatic
diseases (AIRDs), including rheumatoid arthritis and systemic lupus erythematosus …

Systemic lupus erythematosus (SLE) is a heterogeneous disease characterized by the
production of abnormal autoantibodies and immune complexes that can affect the organ and …

Objective Patients with juvenile‐onset systemic lupus erythematosus (JSLE) have increased
atherosclerosis risk. This study investigated novel atherosclerosis progression biomarkers in …

Cardiovascular disease (CVD) is a leading cause of mortality in patients with juvenile-onset
systemic lupus erythematosus (JSLE) associated with atherosclerosis. The interplay …

Juvenile systemic lupus erythematosus (JSLE) is characterised by onset before 18 years of
age and more severe disease phenotype, increased morbidity and mortality compared to …

Aims Apolipoproteins have been reported to be involved in many cardiovascular diseases.
The aim of our study was to investigate the prognostic value of apolipoprotein B (ApoB) to …

CD8+ T cells are cytotoxic lymphocytes that destroy pathogen infected and malignant cells
through release of cytolytic molecules and proinflammatory cytokines. Although the role of …

Cardio-vascular risk (CVR) stratification tools have been implemented in clinical practice to
guide management decision for primary prevention of cardiovascular disease. Less is …

Systemic lupus erythematosus (SLE) is a chronic multi-organ autoimmune disease
characterized by clinical heterogeneity, unpredictable progression, and flare ups. Due to the …