Our understanding of the molecular mechanisms underlying adaptations to resistance
exercise remains elusive despite the significant biological and clinical relevance. We …

Monocytes have been reported to be important mediators of the protective effect of exercise
against the development of Alzheimer's disease (AD). This study aims explored the …

Billions of people have obesity-related metabolic syndromes such as diabetes and
hyperlipidemia. Promoting the browning of white adipose tissue has been suggested as a …

Obesity is a global health crisis that is closely interrelated to many chronic diseases, such as
cardiovascular disease and diabetes. This review provides an in-depth analysis of specific …

Key points Maximal endurance performance is greater in the early daytime. Timed exercise
differentially alters the muscle transcriptome and (phospho)‐proteome. Early daytime …

Traumatic brain injury (TBI) induces a neuroinflammatory response resulting in astrocyte
and microglia activation at the lesion site. This involves upregulation of neuroinflammatory …

The contraction of myotubes using electrical pulse stimulation is a research tool used to
mimic muscle contractile activity and exercise in rodents and humans. Most protocols …

Skeletal muscle is a heterogeneous tissue. Individual myofibers that make up muscle tissue
exhibit variation in their metabolic and contractile properties. Although biochemical and …

The ability of skeletal muscle to adapt to eccentric contractions has been suggested to be
blunted in older muscle. If eccentric exercise is to be a safe and efficient training mode for …

Transcription factors (TFs) play a key role in regulating gene expression and responses to
stimuli. We conducted an integrated analysis of chromatin accessibility, DNA methylation …