Ferroptosis as a promising therapeutic strategy for melanoma

N Ta, X Jiang, Y Zhang, H Wang - Frontiers in pharmacology, 2023 - frontiersin.org
Malignant melanoma (MM) is the most common and deadliest type of skin cancer and is
associated with high mortality rates across all races and ethnicities. Although present …

Post-translational modifications of histone and non-histone proteins in epigenetic regulation and translational applications in alcohol-associated liver disease …

W Rungratanawanich, JW Ballway, X Wang… - Pharmacology & …, 2023 - Elsevier
Epigenetic regulation is a process that takes place through adaptive cellular pathways
influenced by environmental factors and metabolic changes to modulate gene activity with …

Integration of tumor elimination and tissue regeneration via selective manipulation of physiological microenvironments based on intelligent nanocomposite hydrogel …

L Chen, T Yang, L Weng, X Chang, J Liu… - Advanced Functional …, 2023 - Wiley Online Library
Tumor residue and tissue damage normally occurred after surgical treatment of malignant
melanoma, and the effective postoperative therapy is still a challenge because the treatment …

Dendritic cell-derived exosomes driven drug co-delivery biomimetic nanosystem for effective combination of malignant melanoma immunotherapy and gene therapy

J Lin, N Huang, M Li, M Zheng, Z Wang… - Drug Design …, 2023 - Taylor & Francis
Purpose Malignant melanoma (MM), the most lethal skin cancer, is highly invasive and
metastatic. These qualities are related to not only genetic mutations in MM itself but also the …

Celecoxib, a non-steroidal anti-inflammatory drug, exerts a toxic effect on human melanoma cells grown as 2D and 3D cell cultures

A Venuta, R Nasso, A Gisonna, R Iuliano… - Life, 2023 - mdpi.com
Cutaneous melanoma (CM) remains one of the leading causes of tumor mortality due to its
high metastatic spread. CM growth is influenced by inflammation regulated by …

Naturally-derived phenethyl isothiocyanate modulates apoptotic induction through regulation of the intrinsic cascade and resulting apoptosome formation in human …

V Tragkola, I Anestopoulos, S Kyriakou… - Toxicology …, 2024 - Taylor & Francis
Malignant melanoma is the most aggressive type of skin cancer with increasing incidence
rates worldwide. On the other hand, watercress is a rich source of phenethyl isothiocyanate …

Investigation of GPR143 as a promising novel marker for the progression of skin cutaneous melanoma through bioinformatic analyses and cell experiments

R Bai, P Yin, Z Xing, S Wu, W Zhang, X Ma, X Gan… - Apoptosis, 2024 - Springer
Background Skin cutaneous melanoma (SKCM) is an aggressive and life-threatening skin
cancer. G-protein coupled receptor 143 (GPR143) belongs to the superfamily of G protein …

A review: targeting UBR5 domains to mediate emerging roles and mechanisms: chance or necessity?

Y Wang, K Niu, Y Shi, F Zhou, X Li, Y Li… - … Journal of Surgery, 2024 - journals.lww.com
Ubiquitinases are known to catalyze ubiquitin chains on target proteins to regulate various
physiological functions like cell proliferation, autophagy, apoptosis, and cell cycle …

Therapeutic potential of marine peptides in malignant melanoma

S Ahmed, W Alam, KF Alsharif, M Aschner… - Environmental …, 2023 - Elsevier
Malignant melanoma is the most dangerous type of skin cancer. It is becoming more
common globally and is increasingly resistant to treatment options. Despite extensive …

[HTML][HTML] Epigenetics of Conjunctival Melanoma: Current Knowledge and Future Directions

KM Flick, H Demirci, FY Demirci - Cancers, 2024 - mdpi.com
The purpose of this article is to provide a literature review of the epigenetic understanding of
conjunctival melanoma (CM), with a primary focus on current gaps in knowledge and future …