Fatigue, sleep, and autoimmune and related disorders

MR Zielinski, DM Systrom, NR Rose - Frontiers in immunology, 2019 - frontiersin.org
Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Heat of the night: sleep disturbance activates inflammatory mechanisms and induces pain in rheumatoid arthritis

MR Irwin, RH Straub, MT Smith - Nature Reviews Rheumatology, 2023 - nature.com
Sleep has a homeostatic role in the regulation of the immune system and serves to constrain
activation of inflammatory signalling and expression of cellular inflammation. In patients with …

Causal relationship between sleep traits and risk of systemic lupus erythematosus: a two-sample Mendelian randomization study

N Sang, RC Gao, MY Zhang, ZZ Wu, ZG Wu… - Frontiers in …, 2022 - frontiersin.org
A correlation between sleep and systemic lupus erythematosus (SLE) has been observed in
a number of prior investigations. However, little is known regarding the potential causative …

Sleep problems in chronic inflammatory diseases: prevalence, treatment, and new perspectives: a narrative review

M Ditmer, A Gabryelska, S Turkiewicz… - Journal of Clinical …, 2021 - mdpi.com
Epidemiological studies have shown that individuals with sleep problems are at a greater
risk of developing immune and chronic inflammatory diseases. As sleep disorders and low …

Two sides of the same coin? A review of the similarities and differences between idiopathic pulmonary fibrosis and rheumatoid arthritis-associated interstitial lung …

S Matson, J Lee, O Eickelberg - European Respiratory Journal, 2021 - Eur Respiratory Soc
Rheumatoid arthritis associated interstitial lung disease (RA-ILD) and idiopathic pulmonary
fibrosis (IPF) are distinct diseases; however, they share several clinical, radiographic and …

Patients with juvenile idiopathic arthritis are at increased risk for obstructive sleep apnoea: a population-based cohort study

KSK Ma, MM Illescas Ralda… - European Journal of …, 2022 - academic.oup.com
Background and objectives Juvenile idiopathic arthritis (JIA), an autoimmune disease, has
been proposed to be comorbid with obstructive sleep apnoea (OSA). We aimed at testing …

C-reactive protein and risk of OSA in four US cohorts

T Huang, M Goodman, X Li, SA Sands, J Li… - Chest, 2021 - Elsevier
Background Individuals with OSA have elevated levels of inflammatory markers, but no
prospective study has examined the role of inflammation in the development of OSA …

Increased incidence of colorectal cancer with obstructive sleep apnea: a nationwide population-based cohort study

CY Chen, JM Hu, CJ Shen, YC Chou, YF Tian… - Sleep medicine, 2020 - Elsevier
Background Epidemiological studies on the obstructive sleep apnea (OSA) and cancer
relationship in humans are inconsistent. Furthermore, there are limited prospective studies …

Comorbidities as risk factors for rheumatoid arthritis and their accrual after diagnosis

VL Kronzer, CS Crowson, JA Sparks… - Mayo Clinic …, 2019 - Elsevier
Objective To determine the prevalence of comorbidities in rheumatoid arthritis (RA), discover
which comorbidities might predispose to developing RA, and identify which comorbidities …

Family history of rheumatic, autoimmune, and nonautoimmune diseases and risk of rheumatoid arthritis

VL Kronzer, CS Crowson, JA Sparks… - Arthritis care & …, 2021 - Wiley Online Library
Objective Since comorbidities such as autoimmune diseases may be associated with
rheumatoid arthritis (RA) risk, we hypothesized that a family history of these other conditions …