Cerebrovascular diseases such as ischemic stroke, brain hemorrhage, and subarachnoid
hemorrhage provoke cardiac complications such as heart failure, neurogenic stress-related …

The contribution of natural products (NPs) to cardiovascular medicine has been extensively
documented, and many have been used for centuries. Cardiovascular disease (CVD) is the …

Previous studies show that notoginsenoside R1 (NG-R1), a novel saponin isolated from
Panax notoginseng, protects kidney, intestine, lung, brain and heart from ischemia …

Inflammation and apoptosis of vascular endothelial cells play a key role in the occurrence
and development of atherosclerosis (AS), and the AMPK/mTOR/Nrf2 signaling pathway …

Cardiovascular diseases are one of the leading causes of death worldwide and cardiac
fibrosis is a common pathological process for cardiac remodeling in cardiovascular …

Ethnopharmacological relevance Spasmolytic polypeptide-expressing metaplasia (SPEM) is
characterized by mucus cell morphologies at the base of gastric glands, which is considered …

Cardiovascular disease (CVD) remains the major cause of death worldwide, accounting for
almost 31% of the global mortality annually. Several preclinical studies have indicated that …

Ischemic stroke is a syndrome of severe neurological responses that cause neuronal death,
damage to the neurovascular unit and inflammation. Notoginsenoside R1 (NG-R1) is a …

Abstract Notoginsenoside (NG)-R1 is one of the main bioactive compounds from Panax
notoginseng (PN) root, which is well known in the prescription for mediating the micro …

Abstract β2 adrenergic receptor (β2AR) is a G-protein-coupled receptor involved in cardiac
protection. In chronic heart failure (CHF), persistent sympathetic nervous system activation …