Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Staphylococcus aureus is one of the leading hospital-associated and community-associated
pathogens, which has caused a global public health concern. The emergence of methicillin …

The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) result in significant
morbidity and mortality for patients in both community and health care settings. This is …

The development of antibiotic resistance in Staphylococcus aureus, particularly in methicillin-
resistant S. aureus (MRSA), has become a significant health concern worldwide. The …

The history of modern medicine cannot be written apart from the history of the antibiotics.
Antibiotics are cytotoxic secondary metabolites that are isolated from Nature. The …

Antibiotic resistance is a major threat to public health, which contributes largely to increased
mortality rates and costs in hospitals. The severity and widespread nature of antibiotic …

In Staphylococcus aureus, resistance to β-lactamase stable β-lactam antibiotics is mediated
by the penicillinbinding protein 2a, encoded by mecA or by its homologues mecB or mecC …

Methicillin-resistant Staphylococcus aureus isolates lacking mec genes (n= 32), collected
from Belgian hospitals, were characterized for their β-lactamase production and the …

Abstract β-Lactamases (Bla) and low-affinity penicillin-binding proteins (PBP2A) are
responsible for β-lactam resistance in the genera Macrococcus, Mammaliicoccus and …