Epidemiology and treatment of multiple sclerosis in elderly populations

CB Vaughn, D Jakimovski, KS Kavak… - Nature Reviews …, 2019 - nature.com
The prevalence of multiple sclerosis (MS) and the age of affected patients are increasing
owing to increased longevity of the general population and the availability of effective …

Encapsulation of polyphenolic compounds for health promotion and disease prevention: Challenges and opportunities

SA Adefegha, A Salawi, A Bumrungpert… - Nano Micro …, 2022 - nmb-journal.com
Polyphenolic compounds are present in different parts of plants, including the root, stem,
bark, leaves, seeds and fruits. They have been reported for their various biological functions …

Etiology, effects and management of comorbidities in multiple sclerosis: recent advances

RA Marrie, JD Fisk, K Fitzgerald, K Kowalec… - Frontiers in …, 2023 - frontiersin.org
Comorbid conditions commonly affect people with multiple sclerosis (MS). Population-based
studies indicate that people with MS have an increased incidence of ischemic heart disease …

Serum neurofilament light chain level associations with clinical and cognitive performance in multiple sclerosis: A longitudinal retrospective 5-year study

D Jakimovski, R Zivadinov… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: A limited number of studies investigated associations between serum
neurofilament light chain (sNfL) and cognition in persons with multiple sclerosis (PwMS) …

Serum neurofilament light chain levels associations with gray matter pathology: a 5‐year longitudinal study

D Jakimovski, J Kuhle, M Ramanathan… - Annals of clinical …, 2019 - Wiley Online Library
Background Gray matter (GM) pathology is closely associated with physical and cognitive
impairment in persons with multiple sclerosis (PwMS). Similarly, serum neurofilament light …

Alterations in the retinal vasculature occur in multiple sclerosis and exhibit novel correlations with disability and visual function measures

OC Murphy, O Kwakyi, M Iftikhar… - Multiple Sclerosis …, 2020 - journals.sagepub.com
Background: The retinal vasculature may be altered in multiple sclerosis (MS), potentially
acting as a biomarker of disease processes. Objective: To compare retinal vascular plexus …

The ageing central nervous system in multiple sclerosis: the imaging perspective

M Filippi, P Preziosa, F Barkhof, O Ciccarelli… - Brain, 2024 - academic.oup.com
The interaction between ageing and multiple sclerosis is complex and carries significant
implications for patient care. Managing multiple sclerosis effectively requires an …

Atrophied brain T2 lesion volume at MRI is associated with disability progression and conversion to secondary progressive multiple sclerosis

AV Genovese, J Hagemeier, N Bergsland… - Radiology, 2019 - pubs.rsna.org
Background Atrophied T2 lesion volume at MRI is an imaging measure that reflects the
replacement of T2 lesions by cerebrospinal fluid spaces in patients with multiple sclerosis …

Evolution of brain volume loss rates in early stages of multiple sclerosis

T Uher, J Krasensky, C Malpas… - Neurology …, 2021 - AAN Enterprises
Objective To describe the dynamics of brain volume loss (BVL) at different stages of
relapsing-remitting multiple sclerosis (RRMS), to describe the association between BVL and …

Comorbidity is associated with disease activity in MS: findings from the CombiRx trial

A Salter, K Kowalec, KC Fitzgerald, G Cutter… - Neurology, 2020 - AAN Enterprises
Objective To determine whether comorbidity is associated with clinical (relapses, disability
worsening) and MRI outcomes in multiple sclerosis (MS) by conducting a secondary …