Photodynamic therapy for cancer: what's past is prologue

MR Hamblin - Photochemistry and photobiology, 2020 - Wiley Online Library
Abstract Thomas J Dougherty from Roswell Park Cancer Center played a major role in the
progress of photodynamic therapy (PDT) from a laboratory science into a real‐world clinical …

Photodynamic therapy: past, present and future

U Chilakamarthi, L Giribabu - The Chemical Record, 2017 - Wiley Online Library
Though we crossed many milestones in the field of medicine and health care in eradicating
some deadly diseases over the past decades, cancer remained a challenge taking the lives …

Quest for novel chemical entities through incorporation of silicon in drug scaffolds

R Ramesh, DS Reddy - Journal of Medicinal Chemistry, 2017 - ACS Publications
In order to optimize a lead molecule for further development, bioisosteric replacements are
generally adopted as one of the strategies. Silicon appears to be the right choice as a …

Nanoscale metal–organic layer isolates phthalocyanines for efficient mitochondria-targeted photodynamic therapy

GT Nash, T Luo, G Lan, K Ni… - Journal of the American …, 2021 - ACS Publications
Zinc-phthalocyanine (ZnPc) photosensitizers (PSs) have shown great potential in
photodynamic therapy (PDT) owing to their strong absorption at long wavelengths (650–750 …

Enhanced permeability and retention effect: A key facilitator for solid tumor targeting by nanoparticles

VR Shinde, N Revi, S Murugappan, SP Singh… - Photodiagnosis and …, 2022 - Elsevier
Exploring the enhanced permeability and retention (EPR) effect through therapeutic
nanoparticles has been a subject of considerable interest in tumor biology. This passive …

Self-assembled IR780-loaded transferrin nanoparticles as an imaging, targeting and PDT/PTT agent for cancer therapy

K Wang, Y Zhang, J Wang, A Yuan, M Sun, J Wu… - Scientific reports, 2016 - nature.com
Combination of photothermal and photodynamic therapy (PTT/PDT) offer unique
advantages over PDT alone. However, to achieve synergetic PDT/PTT effect, one generally …

Advances in Prostate‐Specific Membrane Antigen (PSMA)‐Targeted Phototheranostics of Prostate Cancer

H Wang, Z He, XA Liu, Y Huang, J Hou… - Small …, 2022 - Wiley Online Library
With the advent of the era of precision medicine, prostate‐specific membrane antigen
(PSMA)‐targeted theranostic strategies have had a profound impact on prostate cancer …

The elements of life and medicines

P Chellan, PJ Sadler - Philosophical Transactions of the …, 2015 - royalsocietypublishing.org
Which elements are essential for human life? Here we make an element-by-element journey
through the periodic table and attempt to assess whether elements are essential or not, and …

European guidelines for topical photodynamic therapy part 1: treatment delivery and current indications–actinic keratoses, Bowen's disease, basal cell carcinoma

CA Morton, RM Szeimies, A Sidoroff… - Journal of the …, 2013 - Wiley Online Library
Topical photodynamic therapy (PDT) is a widely used non‐invasive treatment for certain non‐
melanoma skin cancers, permitting treatment of large and multiple lesions with excellent …

European Dermatology Forum guidelines on topical photodynamic therapy 2019 Part 1: treatment delivery and established indications–actinic keratoses, Bowen's …

CA Morton, RM Szeimies… - Journal of the …, 2019 - Wiley Online Library
Topical photodynamic therapy (PDT) is a widely approved therapy for actinic keratoses,
Bowen's disease (squamous cell carcinoma in situ), superficial and certain thin basal cell …