J Coburn, B Garcia, LT Hu, MW Jewett… - Current issues in …, 2021 - mdpi.com
Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial pathogens that cause disease in humans and non-reservoir vertebrates primarily through …
Lyme disease is the most common vector-borne infectious disease in the United States, in part because a vaccine against it is not currently available for humans. We propose utilizing …
JE Lemieux, W Huang, N Hill, T Cerar… - PLoS …, 2023 - journals.plos.org
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting …
H Hofmann, V Fingerle, KP Hunfeld… - GMS german medical …, 2017 - ncbi.nlm.nih.gov
This guideline of the German Dermatology Society primarily focuses on the diagnosis and treatment of cutaneous manifestations of Lyme borreliosis. It has received consensus from …
JT Skare, BL Garcia - Trends in microbiology, 2020 - cell.com
The complement system is an ancient arm of the innate immune system that plays important roles in pathogen recognition and elimination. Upon activation by microbes, complement …
C Anderson, CA Brissette - Pathogens, 2021 - mdpi.com
Lyme disease (LD) has become the most common vector-borne illness in the northern hemisphere. The causative agent, Borrelia burgdorferi sensu lato, is capable of establishing …
Borrelia burgdorferi, the causative agent of Lyme disease (along with closely related genospecies), is in the deeply branching spirochete phylum. The bacterium is maintained in …
DA Ayón-Núñez, G Fragoso, RJ Bobes… - Bioscience …, 2018 - portlandpress.com
Pathogens have developed particular strategies to infect and invade their hosts. Amongst these strategies' figures the modulation of several components of the innate immune system …
M Strnad, N Rudenko, ROM Rego - Virulence, 2023 - Taylor & Francis
Infection with Borrelia burgdorferi often triggers pathophysiologic perturbations that are further augmented by the inflammatory responses of the host, resulting in the severe clinical …