Recent experimental developments are changing the ways we interpret experimental data in
protein folding, leading to a closer connection with theory and an improved understanding of …

We construct coarse master equations for peptide folding dynamics from atomistic molecular
dynamics simulations. A maximum-likelihood propagator-based method allows us to extract …

For many decades, protein folding experimentalists have worked with no information about
the time scales of relevant protein folding motions and without methods for estimating the …

Recent experimental work on fast protein folding brings about an intriguing paradox.
Microsecond-folding proteins are supposed to fold near or at the folding speed limit …

Using time-resolved IR spectroscopy, we monitored the kinetics of folding and unfolding
processes of a photoswitchable 16-residue alanine-based α-helical peptide on a timescale …

Despite growing evidence suggesting the importance of enzyme conformational dynamics
(ECD) in catalysis, a consensus on how precisely ECD influences the chemical step and …

Intrinsically disordered proteins (IDPs) fold upon binding to select/recruit multiple partners,
morph around the partner's structure, and exhibit allostery. However, we do not know …

Theoretical models have often modeled protein folding dynamics as diffusion on a low-
dimensional free energy surface, a remarkable simplification. However, the accuracy of such …

The realization that folding free energy barriers can be small enough to result in significant
population of the species at the barrier top has sprouted in several methods to estimate …

Dynamics on free energy surfaces with high activation barriers are usually treated by few‐
state kinetics models, yielding characteristic rate coefficients and amplitudes depending on …