Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Rationally engineered nucleic acid architectures for biosensing applications

M Xiao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Advanced liquid biopsy technologies for circulating biomarker detection

N Soda, BHA Rehm, P Sonar, NT Nguyen… - Journal of Materials …, 2019 - pubs.rsc.org
Liquid biopsy is a new diagnostic concept that provides important information for monitoring
and identifying tumor genomes in body fluid samples. Detection of tumor origin …

CRISPR-Cas13 system as a promising and versatile tool for cancer diagnosis, therapy, and research

F Palaz, AK Kalkan, O Can, AN Demir… - ACS Synthetic …, 2021 - ACS Publications
Over the past decades, significant progress has been made in targeted cancer therapy. In
precision oncology, molecular profiling of cancer patients enables the use of targeted cancer …

Nanobiosensors: Point-of-care approaches for cancer diagnostics

R Shandilya, A Bhargava, N Bunkar, R Tiwari… - Biosensors and …, 2019 - Elsevier
Early cancer diagnosis is of prime importance as it paves the way for effective treatment and
possible patient survival. The recent advancements in the field of biosensorics have …

Toward personalized nanomedicine: the critical evaluation of micro and nanodevices for cancer biomarker analysis in liquid biopsy

K Clack, N Soda, S Kasetsirikul, RG Mahmudunnabi… - Small, 2023 - Wiley Online Library
Liquid biopsy for the analysis of circulating cancer biomarkers (CBs) is a major
advancement toward the early detection of cancer. In comparison to tissue biopsy …

Beyond the capture of circulating tumor cells: next‐generation devices and materials

BJ Green, T Saberi Safaei, A Mepham… - Angewandte Chemie …, 2016 - Wiley Online Library
Over the last decade, significant progress has been made towards the development of
approaches that enable the capture of rare circulating tumor cells (CTCs) from the blood of …

Direct plasmon-enhanced electrochemistry for enabling ultrasensitive and label-free detection of circulating tumor cells in blood

SS Wang, XP Zhao, FF Liu, MR Younis, XH Xia… - Analytical …, 2019 - ACS Publications
In this work, we developed a simple electrochemical method for ultrasensitive and label-free
detection of circulating tumor cells (CTCs) based on direct plasmon-enhanced …

Nucleic acid-based electrochemical nanobiosensors

A Abi, Z Mohammadpour, X Zuo, A Safavi - Biosensors and Bioelectronics, 2018 - Elsevier
The detection of biomarkers using sensitive and selective analytical devices is critically
important for the early stage diagnosis and treatment of diseases. The synergy between the …

Advances in diagnostic microfluidics

A Burklund, A Tadimety, Y Nie, N Hao… - Advances in clinical …, 2020 - Elsevier
Microfluidics is an emerging field in diagnostics that allows for extremely precise fluid control
and manipulation, enabling rapid and high-throughput sample processing in integrated …