Probiotics mechanism of action on immune cells and beneficial effects on human health

C Mazziotta, M Tognon, F Martini, E Torreggiani… - Cells, 2023 - mdpi.com
Immune cells and commensal microbes in the human intestine constantly communicate with
and react to each other in a stable environment in order to maintain healthy immune …

Microbiome-based therapeutics

MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

The microbiome and human cancer

GD Sepich-Poore, L Zitvogel, R Straussman, J Hasty… - Science, 2021 - science.org
BACKGROUND Historical accounts linking cancer and microbes date as early as four
millennia ago. After establishment of the germ theory of infectious diseases, clinical research …

[HTML][HTML] Gut microbiome: profound implications for diet and disease

RD Hills, BA Pontefract, HR Mishcon, CA Black… - Nutrients, 2019 - mdpi.com
The gut microbiome plays an important role in human health and influences the
development of chronic diseases ranging from metabolic disease to gastrointestinal …

The human gut microbiome: from association to modulation

TSB Schmidt, J Raes, P Bork - Cell, 2018 - cell.com
Our understanding of the human gut microbiome continues to evolve at a rapid pace, but
practical application of thisknowledge is still in its infancy. This review discusses the type of …

An engineered E. coli Nissle improves hyperammonemia and survival in mice and shows dose-dependent exposure in healthy humans

CB Kurtz, YA Millet, MK Puurunen… - Science translational …, 2019 - science.org
The intestine is a major source of systemic ammonia (NH3); thus, capturing part of gut NH3
may mitigate disease symptoms in conditions of hyperammonemia such as urea cycle …

Application of advanced oxidation processes followed by different treatment technologies for hospital wastewater treatment

AH Khan, NA Khan, S Ahmed, A Dhingra… - Journal of Cleaner …, 2020 - Elsevier
Hospital effluents are the sources for complex high percentage of micropollutants and till
date no specific treatment have been investigated for the removal of pollutants. These …

Enhancing the tropism of bacteria via genetically programmed biosensors

T Chien, T Harimoto, B Kepecs, K Gray… - Nature biomedical …, 2022 - nature.com
Engineered bacteria for therapeutic applications would benefit from control mechanisms that
confine the growth of the bacteria within specific tissues or regions in the body. Here we …

The impact of environmental chemicals on the gut microbiome

K Chiu, G Warner, RA Nowak, JA Flaws… - Toxicological …, 2020 - academic.oup.com
Since the surge of microbiome research in the last decade, many studies have provided
insight into the causes and consequences of changes in the gut microbiota. Among the …

Colibactin: more than a new bacterial toxin

T Faïs, J Delmas, N Barnich, R Bonnet, G Dalmasso - Toxins, 2018 - mdpi.com
Cyclomodulins are bacterial toxins that interfere with the eukaryotic cell cycle. A new
cyclomodulin called colibactin, which is synthetized by the pks genomic island, was …