Foods rich in ellagic tannins are first hydrolyzed into ellagic acid in the stomach and small
intestine, and then converted into urolithins with high bioavailability by the intestinal flora …

Cancer as a disease continues to ravage the world population without regard to sex, age,
and race. Due to the growing number of cases worldwide, cancer exerts a significant …

Urolithins, metabolites produced by the gut microbiota from the polyphenols ellagitannins
and ellagic acid, are discovered by the research group in humans almost 20 years ago …

Urolithin (Uro) B is a natural compound produced by gut bacteria from ingested ellagitannins
(ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranates …

Background N‐4 cytidine acetylation (ac4C) is an epitranscriptomics modification catalyzed
by N‐acetyltransferase 10 (NAT10); important for cellular mRNA stability, rRNA biogenesis …

Urolithin A (UroA) is a gut metabolite produced from ellagic acid-containing foods such as
pomegranates, berries, and walnuts. UroA is of growing interest due to its therapeutic …

Recently, we reported that N-acetyltransferase 10 (NAT10) regulates fatty acid metabolism
through ac4C-dependent RNA modification of key genes in cancer cells. During this work …

Consumption of nuts and berries are considered part of a healthy eating pattern. Nuts and
berries contain a complex nutrient profile, consisting of essential vitamins and minerals …

Diabetes remains one of the leading causes of deaths and co-morbidities in the world, with
tremendous human, social and economic costs. Therefore, despite therapeutics and …

Remodelin is a small molecule inhibitor of N‐acetyltransferase 10 (NAT10), reported to
reverse the effect of cancer conditions such as epithelial to mesenchymal transition, hypoxia …