Apparent changes in the epidemiology and severity of multiple sclerosis

N Koch-Henriksen, M Magyari - Nature Reviews Neurology, 2021 - nature.com
Multiple sclerosis (MS) is an immunological disease that causes acute inflammatory lesions
and chronic inflammation in the CNS, leading to tissue damage and disability. As awareness …

[HTML][HTML] Brain health: time matters in multiple sclerosis

G Giovannoni, H Butzkueven, S Dhib-Jalbut… - Multiple sclerosis and …, 2016 - Elsevier
Introduction We present international consensus recommendations for improving diagnosis,
management and treatment access in multiple sclerosis (MS). Our vision is that these will be …

Epidemiology of multiple sclerosis

J Howard, S Trevick, DS Younger - Neurologic clinics, 2016 - neurologic.theclinics.com
The Americas In 2007, Poser and Brinar 1 noted that published prevalence rates of multiple
sclerosis (MS) could be misleading with the reliance on clinical information and brain MRI …

Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria

CH Polman, SC Reingold, B Banwell… - Annals of …, 2011 - Wiley Online Library
New evidence and consensus has led to further revision of the McDonald Criteria for
diagnosis of multiple sclerosis. The use of imaging for demonstration of dissemination of …

Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

CH Polman, SC Reingold, G Edan… - Annals of Neurology …, 2005 - Wiley Online Library
New diagnostic criteria for multiple sclerosis integrating magnetic resonance image
assessment with clinical and other paraclinical methods were introduced in 2001. The …

The diagnosis of multiple sclerosis and the various related demyelinating syndromes: a critical review

D Karussis - Journal of autoimmunity, 2014 - Elsevier
Multiple sclerosis (MS), is a chronic disease of the central nervous system (CNS)
characterized by loss of motor and sensory function, that results from immune-mediated …

Clinically isolated syndromes suggestive of multiple sclerosis, part I: natural history, pathogenesis, diagnosis, and prognosis

D Miller, F Barkhof, X Montalban, A Thompson… - The Lancet …, 2005 - thelancet.com
In 85% of young adults with multiple sclerosis (MS), onset is a subacute clinically isolated
syndrome (CIS) of the optic nerves, brainstem, or spinal cord. Methods of assessing the …

The epidemiology of multiple sclerosis: insights to disease pathogenesis

DS Goodin - Handbook of clinical neurology, 2014 - Elsevier
The purpose of studying the epidemiology of multiple sclerosis (MS) is twofold. First, it is
important to understand clearly the natural history of the illness in order to assist patients in …

Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes

L Kappos, CH Polman, MS Freedman, G Edan… - Neurology, 2006 - AAN Enterprises
Objective: To assess efficacy, safety, and tolerability of every-other-day interferon beta-1b
treatment in patients with a first clinical event suggestive of multiple sclerosis (MS)(clinically …

Multiple sclerosis: diagnosis, differential diagnosis, and clinical presentation

JM Gelfand - Handbook of clinical neurology, 2014 - Elsevier
The diagnosis of multiple sclerosis (MS) is based on demonstrating evidence of
inflammatory-demyelinating injury within the central nervous system that is disseminated in …