Recent technological advances have enabled the detection and detailed characterization of
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from …

Circulating tumor cells (CTCs) are a major contributor of cancer metastases and hold a
promising prognostic significance in cancer detection. Performing functional and molecular …

Isolation of circulating tumor cells (CTCs) from peripheral blood has the potential to provide
a far easier “liquid biopsy” than tumor tissue biopsies, to monitor tumor cell populations …

The primary cause of tumor-related death in breast cancer (BC) is still represented by distant
metastasization. The dissemination of tumor cells from the primary tumor to distant sites …

Pancreatic cancer is a lethal condition with a rising incidence and often presents at an
advanced stage, contributing to abysmal five-year survival rates. Unspecific symptoms and …

Despite the advancements made in the diagnosis and treatment of cancer, the stages
associated with metastasis remain largely incurable and represent the primary cause of …

Metastasis is the main cause of death in patients with cancer. The molecular mechanisms
underlying the different metastasis steps are not yet fully known, partly because most studies …

Pancreatic ductal adenocarcinoma (PDAC) is the most frequent pancreatic cancer type,
characterized by a dismal prognosis due to late diagnosis, frequent metastases, and limited …

Background: Pancreatic ductal adenocarcinoma (PDAC) requires multimodal therapeutic
approaches and disease monitoring for effective treatment. Liquid biopsy biomarkers …

The main issue concerning localized prostate cancers is the lack of a suitable marker which
could help patients' stratification at diagnosis and distinguish those with a benign disease …