The scanning model for eukaryotic mRNA translation initiation states that the small
ribosomal subunit, along with initiation factors, binds at the cap structure at the 5′ end of …

Background: Hedgehog signaling pathway is a developmental pathway mostly inactive in
adult tissues, with the exception of stem cells. It is often found upregulated in various tumors …

Alternative splicing (AS) promotes transcriptome and proteome diversity during growth,
development, and stress responses in eukaryotes. Genome-wide studies of AS in sugarcane …

The 5ʹ-UTR of the actin-related protein 2/3 complex subunit 2 (ARPC2) mRNA exists in two
variants. Using a bicistronic reporter construct, the present study demonstrates that the …

Simple Summary Nevoid basal cell carcinoma syndrome (NBCCS) is a genetic disorder of
autosomal dominant inheritance that dramatically predisposes a patient to the formation of …

Background Antarctic fishes of the Notothenioidei suborder constitutively upregulate multiple
inducible chaperones, a highly derived adaptation that preserves proteostasis in extreme …

Introduction: Drug transporters are large transmembrane proteins which catalyse the
movement of a wide variety of chemicals, including drugs as well as xeno-and endobiotics …

Pathway activity assessment-based approaches are becoming highly influential in various
fields of biology and medicine. However, these approaches mostly rely on analysis of mRNA …

过氧化物酶体增殖物激活受体γ (peroxisome proliferator-activated receptor gamma, PPARγ)
是脂肪生成的关键调控因子. 本实验室前期研究发现, 与人和鼠等哺乳动物PPARγ …

CDKL5 is a protein kinase with important functions, acting as transcriptional regulator in the
nucleus, modulating the cell cycle and apoptosis, and sensing DNA damages. This kinase …