Saturated five-membered thiazolidines and their derivatives: from synthesis to biological applications

N Sahiba, A Sethiya, J Soni, DK Agarwal… - Topics in Current …, 2020 - Springer
In past decades, interdisciplinary research has been of great interest for scholars.
Thiazolidine motifs behave as a bridge between organic synthesis and medicinal chemistry …

Thiazolidinones: Synthesis, reactivity, and their biological applications

S Nirwan, V Chahal, R Kakkar - Journal of Heterocyclic …, 2019 - Wiley Online Library
Thiazolidinone is a biologically important five‐membered heterocyclic ring having almost all
types of biological activities. This review covers various types of thiazolidinones, such as 2 …

New mononuclear Fe (III), Co (II), Ni (II), Cu (II), and Zn (II) complexes incorporating 4‐{[(2 hydroxyphenyl) imino] methyl} phenyl‐4‐methylbenzenesulfonate (HL) …

NAA Elkanzi, AM Ali, H Hrichi… - Applied Organometallic …, 2022 - Wiley Online Library
Herein, new Fe (III), Co (II), Ni (II), Cu (II), and Zn (II) complexes incorporating 4‐{[(2‐
hydroxyphenyl) imino] methyl} phenyl 4‐methylbenzenesulfonate Schiff‐base ligand (HL) …

Antibiofilm and anticancer activities of unripe and ripe Azadirachta indica (neem) seed extracts

KC Guchhait, T Manna, M Barai, M Karmakar… - … medicine and therapies, 2022 - Springer
Background Antibiotic resistances of pathogens and breast cancer warrant the search for
new alternative strategies. Phytoextracts can eradicate microbe-borne diseases as well as …

New benzothiazole-based thiazolidinones as potent antimicrobial agents. Design, synthesis and biological evaluation

M Haroun, C Tratrat, K Kositzi, E Tsolaki… - Current topics in …, 2018 - ingentaconnect.com
Background: Thiazole and benzothiazole derivatives, as well as thiazolidinones are very
important scaffolds in medicinal chemistry. Literature has revealed that they possess a wide …

Novel imidazo[2,1‐b]thiazole‐based anticancer agents as potential focal adhesion kinase inhibitors: Synthesis, in silico and in vitro evaluation

F Başoğlu, N Ulusoy‐Güzeldemirci… - Chemical Biology & …, 2021 - Wiley Online Library
The purpose of this study was to synthesize imidazo [2, 1‐b] thiazole derivatives,
characterize them with spectroscopical techniques and investigate for cytotoxic and …

Recent advances in synthetic strategies and SAR of thiazolidin-4-one containing molecules in cancer therapeutics

A Sharma, D Sharma, N Saini, SV Sharma… - Cancer and Metastasis …, 2023 - Springer
Cancer is one of the life-threatening diseases accountable for millions of demises globally.
The inadequate effectiveness of the existing chemotherapy and its harmful effects has …

Recent advances in the synthesis of five‐and six‐membered heterocycles as bioactive skeleton: A concise overview

N Jangir, Poonam, S Dhadda, DK Jangid - ChemistrySelect, 2022 - Wiley Online Library
Heterocyclic compounds play a tremendous role in the field of medicinal chemistry due to
their association with diverse pharmacological properties. Most of the pharmaceutical drugs …

4-Thiazolidinone derivatives: synthesis, antimicrobial, anticancer evaluation and QSAR studies

A Deep, B Narasimhan, SM Lim, K Ramasamy… - RSC …, 2016 - pubs.rsc.org
A series of 4-thiazolidinone derivatives (1–18) was synthesized and tested in vitro for its
antimicrobial and anticancer potential. Synthesized compounds were found to be 5 more …

Synthesis and Identification of New N,N-Disubstituted Thiourea, and Thiazolidinone Scaffolds Based on Quinolone Moiety as Urease Inhibitor

YAMM Elshaier, AA Aly, M Abdel-Aziz, HM Fathy… - Molecules, 2022 - mdpi.com
Synthesis of thiazolidinone based on quinolone moiety was established starting from 4-
hydroxyquinol-2-ones. The strategy started with the reaction of ethyl bromoacetate with 4 …