The aldol reaction is one of the most important methods for the stereoselective construction
of polyketide natural products, not only for nature but also for synthetic chemistry. The …

The formation of carbon±carbon or carbon±heteroatom bonds adjacent to a carbonyl group
in a regio-, diastereoand enantioselective manner is one of the most important procedures in …

The directed aldol reaction allows the construction of new carbon–carbon bonds in a regio‐,
diastereo‐, and enantioselective manner. The kinetically controlled, boron‐mediated aldol …

A practical stereocontrolled synthesis of (+)-discodermolide (1) has been completed in
10.3% overall yield (23 steps longest linear sequence). The absolute stereochemistry of the …

High levels of 1, 5-stereoinduction are obtained in the boron-mediated aldol reactions of β-
oxygenated methyl ketones 5, 7 and 8 with achiral aldehydes. The aldol products undergo …

Marine natural products - Natural Product Reports (RSC Publishing) DOI:10.1039/A815113Y
Royal Society of Chemistry View PDF Version DOI: 10.1039/A815113Y (Paper) Reference …

Marine polypropionates Page 1 Marine polypropionates Michael T. Davies-Colemana and Mary
J. Garsonb aDepartment of Chemistry, Rhodes University, Grahamstown 6140, South Africa† …

The selective formation of bondings between molecules is one of the major challenges in
organic chemistry, and the so-called aldol reaction is one of the most important for this …

Covering: 1993 to 2007 Initially isolated in trace quantities from deep-sea sponges, the
structurally related polyketides discodermolide and dictyostatin share the same microtubule …

The total synthesis of the natural product RK-397 is based on a new synthetic strategy for
assembling polyacetate structures, by efficient cross-coupling of nucleophilic terminal alkyne …