Determining the role of microRNAs in psychiatric disorders
Recent studies have revealed that patients with psychiatric disorders have altered
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
microRNA (miRNA) expression profiles in the circulation and brain. Furthermore, animal …
Cannabidiol as a potential treatment for anxiety and mood disorders: molecular targets and epigenetic insights from preclinical research
Cannabidiol (CBD) is the most abundant non-psychoactive component of cannabis; it
displays a very low affinity for cannabinoid receptors, facilitates endocannabinoid signaling …
displays a very low affinity for cannabinoid receptors, facilitates endocannabinoid signaling …
Psychiatric disorders associated with immune checkpoint inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database
Background With the increasing use of immune checkpoint inhibitors (ICIs) for tumour
immunotherapy, the immune-related adverse events (irAEs) caused by their collateral effect …
immunotherapy, the immune-related adverse events (irAEs) caused by their collateral effect …
The microbiome regulates amygdala-dependent fear recall
The amygdala is a key brain region that is critically involved in the processing and
expression of anxiety and fear-related signals. In parallel, a growing number of preclinical …
expression of anxiety and fear-related signals. In parallel, a growing number of preclinical …
Microbial regulation of microRNA expression in the amygdala and prefrontal cortex
Background There is growing evidence for a role of the gut microbiome in shaping
behaviour relevant to many psychiatric and neurological disorders. Preclinical studies using …
behaviour relevant to many psychiatric and neurological disorders. Preclinical studies using …
Neuromuscular synaptogenesis: coordinating partners with multiple functions
H Darabid, AP Perez-Gonzalez… - Nature Reviews …, 2014 - nature.com
The formation of highly efficient and reliable synapses at the neuromuscular junction (NMJ)
relies on dynamic molecular interactions. Studies of the development and maturation of the …
relies on dynamic molecular interactions. Studies of the development and maturation of the …
The roles of the gut microbiota–miRNA interaction in the host pathophysiology
M Li, WD Chen, YD Wang - Molecular Medicine, 2020 - Springer
The gut microbiota regulates the biological processes of organisms acting like
'another'genome, affecting the health and disease of the host. MicroRNAs, as important …
'another'genome, affecting the health and disease of the host. MicroRNAs, as important …
MicroRNA‑34a‑5p expression in the plasma and in its extracellular vesicle fractions in subjects with Parkinson's disease: An exploratory study
Parkinson's disease (PD) is an important disabling age‑related disorder and is the second
most common neurodegenerative disease. Currently, no established molecular biomarkers …
most common neurodegenerative disease. Currently, no established molecular biomarkers …
Epigenetic mechanisms underlying learning and the inheritance of learned behaviors
Gene expression and regulation is an important sculptor of the behavior of organisms.
Epigenetic mechanisms regulate gene expression not by altering the genetic alphabet but …
Epigenetic mechanisms regulate gene expression not by altering the genetic alphabet but …
A neuroscientist's guide to transgenic mice and other genetic tools
The past decade has produced an explosion in the number and variety of genetic tools
available to neuroscientists, resulting in an unprecedented ability to precisely manipulate …
available to neuroscientists, resulting in an unprecedented ability to precisely manipulate …