Isolated atoms featuring unique reactivity are at the heart of enzymatic and homogeneous
catalysts. In contrast, although the concept has long existed, single-atom heterogeneous …

Covalent organic frameworks (COFs) are one of the most important and dynamic members
of the porous organic materials and are constructed using reticular chemistry with the …

Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Enantioselective synthesis with small-molecule chiral hydrogen-bond donors has emerged
as a frontier of research in the field of asymmetric catalysis. Organic chemists have …

This review covers reactions where iminium ions are likely to be active intermediates in the
catalytic cycle. The focus of the review is on synthetically useful protocols and smallmolecule …

In recent years, the concept of combining transition metal catalysis and organocatalysis has
emerged as a promising strategy for developing new and valuable reactions, and has …

Hydrogen bond catalysis and Brønsted acid catalysis are rapidly growing areas in
organocatalysis. A number of chiral acid catalysts has been developed recently. Recent …

The cyclopentenone unit is a very powerful synthon for the synthesis of a variety of bioactive
target molecules. This is due to the broad diversity of chemical modifications available for …

Hydrogen-bonding interaction plays a crucial role in the molecular recognition and
activation processes of various biologically important reactions that are mediated by …

We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an
1, 2-amino alcohol in expectation of their synchronous activation of a nucleophile and an …