Restless legs syndrome

M Manconi, D Garcia-Borreguero… - Nature reviews Disease …, 2021 - nature.com
Restless legs syndrome (RLS) is a common sensorimotor disorder characterized by an urge
to move that appears during rest or is exacerbated by rest, that occurs in the evening or night …

Repetitive transcranial magnetic stimulation in primary sleep disorders

G Lanza, F Fisicaro, M Cantone, M Pennisi… - Sleep medicine …, 2023 - Elsevier
Repetitive transcranial magnetic stimulation (rTMS) is a widely used non-invasive
neuromodulatory technique. When applied in sleep medicine, the main hypothesis …

Sleep and homeostatic control of plasticity

G Lanza, LM DelRosso, R Ferri - Handbook of clinical neurology, 2022 - Elsevier
Sleep homeostasis is a complex neurobiologic phenomenon involving a number of
molecular pathways, neurotransmitter release, synaptic activity, and factors modulating …

New insights into the neurobiology of restless legs syndrome

S Ferré, D García-Borreguero, RP Allen… - The …, 2019 - journals.sagepub.com
Restless legs syndrome (RLS) is a common sensorimotor disorder, whose basic
components include a sensory experience, akathisia, and a sleep-related motor sign …

Update on restless legs syndrome: from mechanisms to treatment

P Gonzalez-Latapi, R Malkani - Current neurology and neuroscience …, 2019 - Springer
Abstract Purpose of Review To provide an overview of the molecular pathways and recent
genetic risk loci associated with restless legs syndrome/Willis-Ekbom disease (RLS/WED) …

Neurophysiological aspects of REM sleep behavior disorder (RBD): a narrative review

M Figorilli, G Lanza, P Congiu, R Lecca, E Casaglia… - Brain sciences, 2021 - mdpi.com
REM sleep without atonia (RSWA) is the polysomnographic (PSG) hallmark of rapid eye
movement (REM) sleep behavior disorder (RBD), a feature essential for the diagnosis of this …

The Effect of sequential bilateral low‐frequency rTMS over dorsolateral prefrontal cortex on serum level of BDNF and GABA in patients with primary insomnia

J Feng, Q Zhang, C Zhang, Z Wen… - Brain and Behavior, 2019 - Wiley Online Library
Objective This study aimed to investigate the effect of sequential bilateral low‐frequency
repetitive transcranial magnetic stimulation (rTMS) over dorsolateral prefrontal cortex …

Central and peripheral nervous system excitability in restless legs syndrome

G Lanza, CG Bachmann, I Ghorayeb, Y Wang, R Ferri… - Sleep medicine, 2017 - Elsevier
Neurophysiological techniques have been applied in restless legs syndrome (RLS) to obtain
direct and indirect measures of central and peripheral nervous system excitability, as well as …

Clinical and electrophysiological impact of repetitive low-frequency transcranial magnetic stimulation on the sensory–motor network in patients with restless legs …

G Lanza, M Cantone, D Aricò… - Therapeutic …, 2018 - journals.sagepub.com
Background: Based on the hyperexcitability and disinhibition observed in patients with
restless legs syndrome (RLS) following transcranial magnetic stimulation (TMS), we …

The neurophysiology of hyperarousal in restless legs syndrome: Hints for a role of glutamate/GABA

G Lanza, R Ferri - Advances in pharmacology, 2019 - Elsevier
Restless legs syndrome (RLS) is a common sensory-motor circadian disorder, whose basic
components include urge to move the legs, unpleasant sensory experience, and periodic …