The view of long noncoding RNAs as nonfunctional “garbage” has been definitely outdated by the large body of evidence indicating this class of ncRNAs as “golden junk”, especially in …
R Heery, SP Finn, S Cuffe, SG Gray - Cancers, 2017 - mdpi.com
Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal- like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …
C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to thousands of nucleotides. There are several major types of functional lncRNAs which …
Oral squamous cell carcinoma (OSCC) is characterized by genomic and epigenomic alterations. However, the mechanisms underlying oral squamous cell carcinoma …
Gastric cancer as a common human malignancy has been associated with aberrant expressions of several coding and non-coding genes. Long non-coding RNAs (lncRNAs) as …
Z You, C Liu, C Wang, Z Ling, Y Wang, Y Wang… - Molecular cancer …, 2019 - AACR
Accumulated evidence indicates that CCAT1 functions as an oncogene in the progression of a variety of tumors. However, little is known as to how CCAT1 impacts tumorigenesis in …
Our previous study has showed doublecortin like kinase 1 (DCLK1) serves as an oncogene to regulate basal-like breast cancer cell proliferation, migration and invasion, and is …
T Wu, Y Du - International journal of biological sciences, 2017 - ncbi.nlm.nih.gov
This review aimed to summarize the current research contents about long noncoding RNAs (lncRNAs) and some related lncRNAs as molecular biomarkers or therapy strategies in …
Z Liu, QJ Chen, SS Hann - Biomedicine & Pharmacotherapy, 2019 - Elsevier
In various human cancers, long non-coding RNAs (lncRNAs), a novel class of RNAs longer than 200 nucleotides without protein-coding potential, are implicated in a variety of …