Noncoding RNAs regulate alternative splicing in Cancer

Y Liu, X Liu, C Lin, X Jia, H Zhu, J Song… - Journal of Experimental & …, 2021 - Springer
AS (alternative splicing) is a fundamental process by which a gene can generate multiple
distinct mRNA transcripts to increase protein diversity. Defects in AS influence the …

Emerging role of oncogenic long noncoding RNA as cancer biomarkers

M Aprile, V Costa, A Cimmino… - International journal of …, 2023 - Wiley Online Library
The view of long noncoding RNAs as nonfunctional “garbage” has been definitely outdated
by the large body of evidence indicating this class of ncRNAs as “golden junk”, especially in …

Long non-coding RNAs: key regulators of epithelial-mesenchymal transition, tumour drug resistance and cancer stem cells

R Heery, SP Finn, S Cuffe, SG Gray - Cancers, 2017 - mdpi.com
Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …

LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years

C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to
thousands of nucleotides. There are several major types of functional lncRNAs which …

Emerging role of non-coding RNA in oral cancer

F Momen-Heravi, S Bala - Cellular signalling, 2018 - Elsevier
Oral squamous cell carcinoma (OSCC) is characterized by genomic and epigenomic
alterations. However, the mechanisms underlying oral squamous cell carcinoma …

Long non-coding RNA signature in gastric cancer

S Ghafouri-Fard, M Taheri - Experimental and Molecular Pathology, 2020 - Elsevier
Gastric cancer as a common human malignancy has been associated with aberrant
expressions of several coding and non-coding genes. Long non-coding RNAs (lncRNAs) as …

LncRNA CCAT1 promotes prostate cancer cell proliferation by interacting with DDX5 and MIR-28-5P

Z You, C Liu, C Wang, Z Ling, Y Wang, Y Wang… - Molecular cancer …, 2019 - AACR
Accumulated evidence indicates that CCAT1 functions as an oncogene in the progression of
a variety of tumors. However, little is known as to how CCAT1 impacts tumorigenesis in …

[HTML][HTML] miR-424-5p regulates cell proliferation, migration and invasion by targeting doublecortin-like kinase 1 in basal-like breast cancer

J Wang, S Wang, J Zhou, Q Qian - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Our previous study has showed doublecortin like kinase 1 (DCLK1) serves as an oncogene
to regulate basal-like breast cancer cell proliferation, migration and invasion, and is …

[HTML][HTML] LncRNAs: from basic research to medical application

T Wu, Y Du - International journal of biological sciences, 2017 - ncbi.nlm.nih.gov
This review aimed to summarize the current research contents about long noncoding RNAs
(lncRNAs) and some related lncRNAs as molecular biomarkers or therapy strategies in …

[HTML][HTML] The functions and oncogenic roles of CCAT1 in human cancer

Z Liu, QJ Chen, SS Hann - Biomedicine & Pharmacotherapy, 2019 - Elsevier
In various human cancers, long non-coding RNAs (lncRNAs), a novel class of RNAs longer
than 200 nucleotides without protein-coding potential, are implicated in a variety of …