[HTML][HTML] Tomatoes, lycopene, and prostate cancer: what have we learned from experimental models?

NE Moran, JM Thomas-Ahner, L Wan, KE Zuniga… - The Journal of …, 2022 - Elsevier
Human epidemiology suggests a protective effect of tomatoes or tomato phytochemicals,
such as lycopene, on prostate cancer risk. However, human epidemiology alone cannot …

[HTML][HTML] Impacts of endocrine-disrupting chemicals on prostate function and cancer

A Lacouture, C Lafront, C Peillex, M Pelletier… - Environmental …, 2022 - Elsevier
Because of their historical mode of action, endocrine-disrupting chemicals (EDCs) are
associated with sex-steroid receptors, namely the two estrogen receptors (ERα and ERβ) …

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes

C Szpirer - Journal of biomedical science, 2020 - Springer
The laboratory rat has been used for a long time as the model of choice in several
biomedical disciplines. Numerous inbred strains have been isolated, displaying a wide …

The targeting of non‑coding RNAs by curcumin: Facts and hopes for cancer therapy

Y Liu, H Sun, B Makabel, Q Cui, J Li… - Oncology …, 2019 - spandidos-publications.com
Abstract Curcumin [(1E, 6E)‑1, 7‑bis (4‑hydroxy‑3‑methoxyphenyl) hepta‑1, 6‑diene‑3, 5‑
dione] is a natural polyphenol that is derived from the turmeric plant (curcuma longa L.) …

Evaluation of a photodynamic therapy agent using a canine prostate cancer model

D Luo, X Wang, G Ramamurthy, E Walker… - The …, 2023 - Wiley Online Library
Background Male dogs can develop spontaneous prostate cancer, which is similar
physiologically to human disease. Recently, Tweedle and coworkers have developed an …

Appraising animal models of prostate cancer for translational research: future directions

E Nascimento-Goncalves, F Seixas… - Anticancer …, 2023 - ar.iiarjournals.org
The growing incidence of prostate cancer has prompted a great investment in basic biology
and translational studies to develop new therapies. Multiple animal models have been …

Histological and biochemical investigation of the renoprotective effects of metformin in diabetic and prostate cancer model

P Koroglu-Aydın, BB Bayrak, I Bugan… - Toxicology …, 2021 - Taylor & Francis
Background Diabetes and cancer have common physiological and biochemical
mechanisms. Metformin is the preferred drug of choice for the treatment of diabetes. Prostate …

[PDF][PDF] Membranes and deoxyribonucleic acid of hippocampal neurons damage due to low-density polyethylene microplastics in blood of Wistar rats

Y Sincihu, IK Sudiana, K Kusumastuti… - … acid of hippocampal …, 2022 - academia.edu
Microplastic particles in the blood can cause damage to organs such as the brain. This study
aimed to analyze the effect of microplastic particles in the blood on membrane damage …

Evolution of models of prostate cancer: Their contribution to current therapies

AI Faustino-Rocha, C Jota-Baptista… - Anticancer …, 2023 - ar.iiarjournals.org
Prostate cancer (PCa) is among the most frequent cancers worldwide. Nowadays, several
therapeutic strategies are available for PCa treatment, namely chemotherapy …

An overview of current alternative models for use in the context of prostate cancer research

E Nascimento-Gonçalves, R Ferreira… - Alternatives to …, 2020 - journals.sagepub.com
Prostate cancer is one of the most commonly diagnosed cancers worldwide, particularly in
elderly populations. To mitigate the expected increase in prostate cancer-related morbidity …