Immune checkpoint inhibition as a therapeutic strategy for HIV eradication: current insights and future directions
J Lee, JB Whitney - Current Opinion in HIV and AIDS, 2024 - journals.lww.com
Although there are very encouraging findings showing enhanced CD8+ T-cell function with
ICI therapy in HIV infection, it remains uncertain whether ICIs alone could demonstrably …
ICI therapy in HIV infection, it remains uncertain whether ICIs alone could demonstrably …
Biotech's role in advancing HIV vaccine development
R Tatoud, C Brander, C Hwang, J Kennelly… - Emerging Microbes & …, 2024 - Taylor & Francis
ABSTRACT HIV vaccine development has been hindered by significant challenges over four
decades. Despite persistent efforts, all efficacy trials to date have yielded disappointing …
decades. Despite persistent efforts, all efficacy trials to date have yielded disappointing …
Recent advances on anti-HIV chimeric antigen receptor-T-cell treatment to provide sustained HIV remission
H Su, A Mueller, H Goldstein - Current Opinion in HIV and AIDS, 2024 - journals.lww.com
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[HTML][HTML] Interventions during Early Infection: Opening a Window for an HIV Cure?
Although combination antiretroviral therapy (ART) has been a landmark achievement for the
treatment of human immunodeficiency virus (HIV), an HIV cure has remained elusive …
treatment of human immunodeficiency virus (HIV), an HIV cure has remained elusive …
[HTML][HTML] Understanding early HIV-1 rebound dynamics following antiretroviral therapy interruption: The importance of effector cell expansion
Most people living with HIV-1 experience rapid viral rebound once antiretroviral therapy is
interrupted; however, a small fraction remain in viral remission for an extended duration …
interrupted; however, a small fraction remain in viral remission for an extended duration …
Super antibodies–bear in mind
SR Hosein - catie.ca
As mentioned earlier in this issue of TreatmentUpdate, there are several super antibodies
(also known as broadly neutralizing antibodies, or bNAb) in development. These are …
(also known as broadly neutralizing antibodies, or bNAb) in development. These are …