[HTML][HTML] Insights into the roles and pathomechanisms of ceramide and sphigosine-1-phosphate in nonalcoholic fatty liver disease

C Zhu, Q Huai, X Zhang, H Dai, X Li… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD), as one of the main causes of chronic liver disease
worldwide, encompasses a spectrum of liver conditions that are not caused by other …

Omics biomarkers and an approach for their practical implementation to delineate health status for personalized nutrition strategies

J Keijer, X Escoté, S Galmés… - Critical reviews in …, 2024 - Taylor & Francis
Personalized nutrition (PN) has gained much attention as a tool for empowerment of
consumers to promote changes in dietary behavior, optimizing health status and preventing …

Role of hepatic lipid species in the progression of nonalcoholic fatty liver disease

KQ Deng, X Huang, F Lei, XJ Zhang… - … of Physiology-Cell …, 2022 - journals.physiology.org
Nonalcoholic fatty liver disease (NAFLD) has become the most common liver disease due to
the global pandemic of metabolic diseases. Dysregulation of hepatic lipid metabolism plays …

Increased hepatic putrescine levels as a new potential factor related to the progression of metabolic dysfunction‐associated steatotic liver disease

MÁ Núñez‐Sánchez… - The Journal of …, 2024 - Wiley Online Library
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a chronic liver condition
that often progresses to more advanced stages, such as metabolic dysfunction‐associated …

Greater hepatic lipid saturation is associated with impaired glycaemic regulation in men with metabolic dysfunction‐associated steatotic liver disease but is not altered …

SA Willis, S Malaikah, SJ Bawden… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aims To examine the impact of impaired glycaemic regulation (IGR) and exercise training on
hepatic lipid composition in men with metabolic dysfunction‐associated steatotic liver …

Endpoints in NASH clinical trials: are we blind in one eye?

A Lonardo, S Ballestri, A Mantovani, G Targher, F Bril - Metabolites, 2024 - mdpi.com
This narrative review aims to illustrate the notion that nonalcoholic steatohepatitis (NASH),
recently renamed metabolic dysfunction-associated steatohepatitis (MASH), is a systemic …

Therapeutic potential of alkaloid extract from Codonopsis Radix in alleviating hepatic lipid accumulation: insights into mitochondrial energy metabolism and …

FAN Cailian, W Guan, C Miao, LI Yao, T Xiyang… - Chinese Journal of …, 2023 - Elsevier
Alkaloids are a class of naturally occurring bioactive compounds that are widely distributed
in various food sources and Traditional Chinese Medicine. This study aimed to investigate …

Effects of Konjac Glucomannan on Weight Management and Liver Health: Insights from Liver Lipidomics in Obese and Nonobese Mice

H Jin, P Xia, Z Deng, T Hou, J Li… - Journal of Agricultural and …, 2024 - ACS Publications
Konjac glucomannan (KGM) is a water-soluble dietary fiber and is used for weight
management. However, there is a lack of research on KGM for weight management in …

Liver lipidomics analysis reveals the anti-obesity and lipid-lowering effects of gypnosides from heat-processed Gynostemma pentaphyllum in high-fat diet fed mice

P Xie, JB Xie, MY Xiao, M Guo, YS Qi, FF Li, XL Piao - Phytomedicine, 2023 - Elsevier
Abstract Background In traditional Chinese medicine, Gynostemma pentaphyllum (G.
pentaphyllum) is widely used to treat conditions associated with hyperlipidemia, and its …

Interaction mechanisms between major depressive disorder and non-alcoholic fatty liver disease

Q Shao, Y Wu, J Ji, T Xu, Q Yu, C Ma, X Liao… - Frontiers in …, 2021 - frontiersin.org
Major depressive disorder (MDD), which is highly associated with non-alcoholic fatty liver
disease (NAFLD), has complex pathogenic mechanisms. However, a limited number of …