Molecular mechanism of hippocampal long-term potentiation–Towards multiscale understanding of learning and memory
Y Hayashi - Neuroscience Research, 2022 - Elsevier
Long-term potentiation (LTP) of synaptic transmission is considered to be a cellular
counterpart of learning and memory. Activation of postsynaptic NMDA type glutamate …
counterpart of learning and memory. Activation of postsynaptic NMDA type glutamate …
Fast and deep phosphoproteome analysis with the Orbitrap Astral mass spectrometer
Owing to its roles in cellular signal transduction, protein phosphorylation plays critical roles
in myriad cell processes. That said, detecting and quantifying protein phosphorylation has …
in myriad cell processes. That said, detecting and quantifying protein phosphorylation has …
A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets
Aptamer-based proteomics revealed differentially abundant proteins in Alzheimer's disease
(AD) brains in the Baltimore Longitudinal Study of Aging and Religious Orders Study (mean …
(AD) brains in the Baltimore Longitudinal Study of Aging and Religious Orders Study (mean …
Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology
NJ Pandya, C Wang, V Costa, P Lopatta, S Meier… - Cell Reports …, 2021 - cell.com
Angelman syndrome (AS) is a neurodevelopmental disorder caused by the loss of maternal
UBE3A, a ubiquitin protein ligase E3A. Here, we study neurons derived from patients with …
UBE3A, a ubiquitin protein ligase E3A. Here, we study neurons derived from patients with …
Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation
The many variants of human Ca2+/calmodulin-dependent protein kinase II (CaMKII) differ in
the lengths and sequences of disordered linkers connecting the kinase domains to the …
the lengths and sequences of disordered linkers connecting the kinase domains to the …
Multiple types of navigational information are independently encoded in the population activities of the dentate gyrus neurons
T Murano, R Nakajima, A Nakao… - Proceedings of the …, 2022 - National Acad Sciences
The dentate gyrus (DG) plays critical roles in cognitive functions, such as learning, memory,
and spatial coding, and its dysfunction is implicated in various neuropsychiatric disorders …
and spatial coding, and its dysfunction is implicated in various neuropsychiatric disorders …
[PDF][PDF] Flexible linkers in CaMKII control the balance between
M Bhattacharyya, YK Lee, S Muratcioglu, B Qiu - scholar.archive.org
The activity of Ca2+/calmodulin-dependent protein kinase II (CaMKII) depends on the
balance between activating and inhibitory autophosphorylation (Thr 286 and Thr 305/306 …
balance between activating and inhibitory autophosphorylation (Thr 286 and Thr 305/306 …
[HTML][HTML] CaMKII の新しいシナプス可塑性機構
林康紀， 細川智永， 劉品吾… - Journal of Japanese …, 2021 - seikagaku.jbsoc.or.jp
Ca 2+/カルモジュリン依存性キナーゼ II (CaMKII) は長期増強現象に必須なキナーゼとして知られ
てきた. しかし, その 12 量体構造の意義や, キナーゼであるのにかかわらずシナプスで最多の …
てきた. しかし, その 12 量体構造の意義や, キナーゼであるのにかかわらずシナプスで最多の …