Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

H Sies, VV Belousov, NS Chandel, MJ Davies… - … reviews Molecular cell …, 2022 - nature.com
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …

NADPH oxidases (NOX): an overview from discovery, molecular mechanisms to physiology and pathology

A Vermot, I Petit-Härtlein, SME Smith, F Fieschi - Antioxidants, 2021 - mdpi.com
The reactive oxygen species (ROS)-producing enzyme NADPH oxidase (NOX) was first
identified in the membrane of phagocytic cells. For many years, its only known role was in …

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

H Sies, DP Jones - Nature reviews Molecular cell biology, 2020 - nature.com
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Oxidative stress: Concept and some practical aspects

H Sies - Antioxidants, 2020 - mdpi.com
Oxidative stress is defined as “an imbalance between oxidants and antioxidants in favor of
the oxidants, leading to a disruption of redox signaling and control and/or molecular …

ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

[HTML][HTML] Oxidative eustress: On constant alert for redox homeostasis

H Sies - Redox Biology, 2021 - Elsevier
In the open metabolic system, redox-related signaling requires continuous monitoring and
fine-tuning of the steady-state redox set point. The ongoing oxidative metabolism is a …

Stable, wavelength‐tunable fluorescent dyes in the NIR‐II region for in vivo high‐contrast bioimaging and multiplexed biosensing

Z Lei, C Sun, P Pei, S Wang, D Li, X Zhang… - Angewandte …, 2019 - Wiley Online Library
Small‐molecule organic fluorophores, spectrally active in the 900–1700 nm region, with
tunable wavelength and sensing properties are sought‐after for in vivo optical imaging and …

Cancer metabolism and tumor microenvironment: fostering each other?

Y Yuan, H Li, W Pu, L Chen, D Guo, H Jiang… - Science China Life …, 2022 - Springer
The changes associated with malignancy are not only in cancer cells but also in
environment in which cancer cells live. Metabolic reprogramming supports tumor cell high …

Lipid peroxidation in osteoarthritis: Focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis

X Zhang, L Hou, Z Guo, G Wang, J Xu, Z Zheng… - Cell Death …, 2023 - nature.com
Osteoarthritis (OA) is a multifactorial and increasingly prevalent degenerative disease that
affects the whole joint. The pathogenesis of OA is poorly understood and there is a lack of …

Activity‐based sensing: a synthetic methods approach for selective molecular imaging and beyond

KJ Bruemmer, SWM Crossley… - Angewandte Chemie …, 2020 - Wiley Online Library
Emerging from the origins of supramolecular chemistry and the development of selective
chemical receptors that rely on lock‐and‐key binding, activity‐based sensing (ABS)—which …