Copper (Cu) is an essential trace element for all living organisms and used as cofactor in
key enzymes of important biological processes, such as aerobic respiration or superoxide …

A general principle in all cells in the body is that an essential metal–here copper–is taken up
at the plasma membrane, directed through cellular compartments for use in specific …

The human transporter ATP7B delivers copper to the biosynthetic pathways and maintains
copper homeostasis in the liver. Mutations in ATP7B cause the potentially fatal …

Bioremediation is one of the most effective ways for removal of heavy metals and restoration
of contaminated sites. This study investigated the copper (Cu) resistance mechanism and …

The formylglycine‐generating enzyme (FGE) is a unique copper protein that catalyzes
oxygen‐dependent C− H activation. We describe 1.66 Å‐and 1.28 Å‐resolution crystal …

PccA and SenC are periplasmic copper chaperones required for the biogenesis of cbb 3-
type cytochrome c oxidase (cbb 3-Cox) in Rhodobacter capsulatus at physiological Cu …

Cu homeostasis depends on a tightly regulated network of proteins that transport or
sequester Cu, preventing the accumulation of this toxic metal while sustaining Cu supply for …

The ability to specifically label the sulphide ions of protein-bound iron–sulphur (FeS)
clusters with 34S isotope greatly facilitates structure–function studies. In particular, it …

CopA is a Cu (I)-exporting transmembrane P 1B-type ATPase from Bacillus subtilis. It
contains two N-terminal cytoplasmic domains, CopAab, which bind Cu (I) with high affinity …

Copper homeostasis in Gram-positive bacteria essentially requires three components: a
copper exporting ATPase (founding member CopA), a copper chaperone (founding member …