The renin-angiotensin system (RAS) is a key player in the control of the cardiovascular
system and hydroelectrolyte balance, with an influence on organs and functions throughout …

The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …

Mid-life hypertension and cerebrovascular dysfunction are associated with increased risk of
later life dementia, including Alzheimer's disease (AD). The classical renin–angiotensin …

The Mas-related G protein–coupled receptors (Mrgprs or Mas-related genes) comprise a
subfamily of receptors named after the first discovered member, Mas. For most Mrgprs …

Renin Angiotensin System (RAS) is a hormonal system that regulates blood pressure and
fluid balance through a coordinated action of renal, cardiovascular, and central nervous …

Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
neuron losses in memory-associated brain structures that rob patients of their dignity and …

Overactivation of angiotensin-converting enzyme/angiotensin 2/angiotensin receptor-1
(ACE/Ang2/AT1) axis provokes amyloid-β-induced apoptosis and neurodegeneration in …

In addition to the classical hormonal (tissue-to-tissue) renin-angiotensin system (RAS), there
are a paracrine (cell-to-cell) and an intracrine (intracellular/nuclear) RAS. A local paracrine …

Over-activation of the brain renin-angiotensin system (RAS) has been implicated in the
etiology of anxiety disorders. Angiotensin converting enzyme 2 (ACE2) inhibits RAS activity …