[HTML][HTML] Enterovirus A71 antivirals: past, present, and future

J Wang, Y Hu, M Zheng - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Abstract Enterovirus A71 (EV-A71) is a significant human pathogen, especially in children.
EV-A71 infection is one of the leading causes of hand, foot, and mouth diseases (HFMD) …

[HTML][HTML] Advances in anti-EV-A71 drug development research

S Wang, Z Pang, H Fan, Y Tong - Journal of Advanced Research, 2024 - Elsevier
Abstract Background Enterovirus A71 (EV-A71) is capable of causing hand, foot and mouth
disease (HFMD), which may lead to neurological sequelae and even death. As EV-A71 is …

Enterovirus D68 antivirals: past, present, and future

Y Hu, R Musharrafieh, M Zheng… - ACS infectious diseases, 2020 - ACS Publications
Enterovirus D68 (EV-D68) is an RNA virus that causes respiratory illnesses mainly in
children. In severe cases, it can lead to neurological complications such as acute flaccid …

Identification of N- and C-3-Modified Laudanosoline Derivatives as Novel Influenza PAN Endonuclease Inhibitors

Y Liao, Y Ye, M Liu, Z Liu, J Wang, B Li… - Journal of Medicinal …, 2022 - ACS Publications
Influenza PAN inhibitors are of particular importance in current efforts to develop a new
generation of antiviral drugs due to the growing emergence of highly pathogenic influenza …

Recent advances in enterovirus A71 infection and antiviral agents

Y Wei, H Liu, D Hu, Q He, C Yao, H Li, K Hu… - Laboratory …, 2023 - Elsevier
Abstract Enterovirus A71 (EV-A71) is one of the major causative agents of hand-foot-and-
mouth disease (HFMD) that majorly affects children. Most of the time, HFMD is a mild …

[HTML][HTML] Rhinovirus inhibitors: Including a new target, the viral RNA

A Real-Hohn, D Blaas - Viruses, 2021 - mdpi.com
Rhinoviruses (RVs) are the main cause of recurrent infections with rather mild symptoms
characteristic of the common cold. Nevertheless, RVs give rise to enormous numbers of …

Management of neonatal central nervous system viral infections: Knowledge gaps and research priorities

M Abeywickrema, D Kelly… - Reviews in Medical …, 2023 - Wiley Online Library
Congenital CMV, enteroviruses, human parechovirus and herpes simplex virus are all
common causes of severe central nervous system (CNS) infection in neonates. The …

[HTML][HTML] A comparative and comprehensive review of antibody applications in the treatment of lung disease

Y Wu, H Song - Life, 2022 - mdpi.com
Antibodies are a type of protein produced by active B cells in response to antigen
stimulation. A series of monoclonal antibodies and neutralizing antibodies have been …

Chemoproteomics enables identification of coatomer subunit zeta‐1 targeted by a small molecule for enterovirus A71 inhibition

X Li, J Zhang, Y Xiao, H Song, Y Li, W Li, R Cao… - MedComm, 2024 - Wiley Online Library
Abstract Human enterovirus A71 (EV‐A71) is a significant etiological agent responsible for
epidemics of hand, foot, and mouth disease (HFMD) in Asia‐Pacific regions. There are …

Antiviral activity of SP81 peptide against Enterovirus A71 (EV-A71)

N Abd-Aziz, MF Lee, SK Ong, CL Poh - Virology, 2024 - Elsevier
The hand, food, and mouth disease (HFMD) is primarily caused by Enterovirus A71 (EV-
A71). EV-A71 outbreaks in the Asia Pacific have been associated with severe neurological …