[HTML][HTML] Novel insights into noncanonical open reading frames in cancer
Y Liu, S Zeng, M Wu - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
With technological advances, previously neglected noncanonical open reading frames
(nORFs) are drawing ever-increasing attention. However, the translation potential of …
(nORFs) are drawing ever-increasing attention. However, the translation potential of …
Streamlined and sensitive mono-and di-ribosome profiling in yeast and human cells
L Ferguson, HE Upton, SC Pimentel, A Mok… - Nature …, 2023 - nature.com
Ribosome profiling has unveiled diverse regulation and perturbations of translation through
a transcriptome-wide survey of ribosome occupancy, read out by sequencing of ribosome …
a transcriptome-wide survey of ribosome occupancy, read out by sequencing of ribosome …
A close-up of regulatory networks and signaling pathways of MKK5 in biotic and abiotic stresses
Abstract Mitogen-activated protein Kinase Kinase 5 (MKK5) is a central hub in the complex
phosphorylation chain reaction of the Mitogen-activated protein kinases (MAPK) cascade …
phosphorylation chain reaction of the Mitogen-activated protein kinases (MAPK) cascade …
[HTML][HTML] Translational buffering by ribosome stalling in upstream open reading frames
TA Bottorff, H Park, AP Geballe… - PLoS genetics, 2022 - journals.plos.org
Upstream open reading frames (uORFs) are present in over half of all human mRNAs.
uORFs can potently regulate the translation of downstream open reading frames through …
uORFs can potently regulate the translation of downstream open reading frames through …
Stable m7G Cap-Distal 5′UTR Hairpin Structure Mediates Distinct 40S and 60S Binding Dynamics
H Wang, A Gaba, X Qu - bioRxiv, 2021 - biorxiv.org
ABSTRACT The 5′ untranslated region (UTR) of diverse mRNAs contains secondary
structures that can influence protein synthesis by modulating the initiation step of translation …
structures that can influence protein synthesis by modulating the initiation step of translation …
m7G cap-eIF4E interaction stimulates polysome formation by enhancing first-round initiation kinetics
L Sun, A Gaba, H Wang, X Qu - bioRxiv, 2021 - biorxiv.org
Translation in eukaryotic cells occurs predominantly through a 7-methylguanosine (m7G)
cap-dependent mechanism. m7G cap interactions with eukaryotic initiation factor 4E (eIF4E) …
cap-dependent mechanism. m7G cap interactions with eukaryotic initiation factor 4E (eIF4E) …