[HTML][HTML] Introducing dysfunctional Protein-Protein Interactome (dfPPI)–a platform for systems-level protein-protein interaction (PPI) dysfunction investigation in disease

S Chakrabarty, S Wang, T Roychowdhury… - Current Opinion in …, 2024 - Elsevier
Protein-protein interactions (PPIs) play a crucial role in cellular function and disease
manifestation, with dysfunctions in PPI networks providing a direct link between stressors …

Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation

T Roychowdhury, SW McNutt, C Pasala… - Nature …, 2024 - nature.com
The intricate network of protein-chaperone interactions is crucial for maintaining cellular
function. Recent discoveries have unveiled the existence of specialized chaperone …

[HTML][HTML] Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation

SW McNutt, T Roychowdhury, C Pasala… - Research …, 2024 - ncbi.nlm.nih.gov
The intricate protein-chaperone network is vital for cellular function. Recent discoveries have
unveiled the existence of specialized chaperone complexes called epichaperomes, protein …