Neutrophils are an essential part of the innate immune system and the first line of defense
against invading pathogens. They phagocytose, release granular contents, produce reactive …

Thrombosis remains a major problem in our society, manifesting across multiple
demographic groups and with high associated morbidity and mortality. Thrombus …

The innate immune system plays an essential role in the response to sterile inflammation
and its association with liver ischemia and reperfusion injury (IRI). Liver IRI often manifests …

Neutrophils were long considered to be a short-lived homogenous cell population, limited to
their role as first responders in anti-bacterial and-fungal immunity. While it is true that …

Abstract Peptide arginine deiminase 2 (PAD2) catalyzes the conversion of arginine residues
on target proteins to citrulline residues in the presence of calcium ions. This particular …

Post-translational modifications (PTMs) of proteins are central to epigenetic regulation and
cellular signalling, playing an important role in the pathogenesis and progression of …

Herpes simplex virus 1 (HSV-1) is a neurotropic virus that remains latent in neuronal cell
bodies but reactivates throughout an individual's life, causing severe adverse reactions …

Infectious and inflammatory stimuli induce the release of neutrophil extracellular traps
(NETs), webs of cell‐free (cf) DNA complexed with histones and antimicrobial proteins, that …

Posttranslational protein modifications (PTMs) are an inherent response to physiological
changes causing altered protein structure and potentially modulating important biological …

Asthma is a common, chronic inflammatory disease of the airways that affects millions of
people worldwide and is associated with significant healthcare costs. Eosinophils, a type of …