Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug
carrier, and the only NP system currently approved by the FDA for clinical use, owing to their …

Disulfiram (DSF) has been used as an alcoholism drug for 70 years. Recently, it has
attracted increasing attention owing to the distinguished anticancer activity, which can be …

Copper (Cu) plays a pivotal role in cancer progression by acting as a co-factor that regulates
the activity of many enzymes and structural proteins in cancer cells. Therefore, Cu-based …

Introduction The application of doxorubicin (DOX) in cancer therapy has been limited due to
its drug resistance and poor internalization. Graphene oxide (GO) nanostructures have the …

Multidrug resistance (MDR) in cancer chemotherapy is a growing concern for medical
practitioners. P-glycoprotein (P-gp) overexpression is one of the major reasons for multidrug …

In the advancement of tumor therapy, in addition to the search for new antitumor
compounds, the development of nano-drug delivery systems has opened up new pathways …

Doxorubicin (DOX) is a natural antibiotic with antineoplastic activity. It has been used for
over 40 years and remains one of the most used drugs in chemotherapy for a variety of …

Cancer, as one of the most challenging diseases of the last century, has a significant
number of patients and deaths every year. Various strategies have been explored for the …

Nanoparticle mediated hyperthermia has been explored as a method to increase cancer
treatment efficacy by heating tumours inside-out. With that purpose, nanoparticles have …