Adult pluripotent stem cell (aPSC) populations underlie whole-body regeneration in many
distantly-related animal lineages, but how the underlying cellular and molecular …

Extracellular matrix (ECM) is an important component of stem cell niche. Remodeling of
ECM mediated by ECM regulators, such as matrix metalloproteinases (MMPs) plays a vital …

Successful regeneration of missing tissues requires seamless integration of positional
information along the body axes. Planarians, which regenerate from almost any injury, use …

In recent years, the role of liquid–liquid phase separation (LLPS) and intrinsically disordered
proteins (IDPs) in cellular molecular processes has received increasing attention from …

Regeneration abilities are widespread among animals and select species can restore any
body parts removed by wounds that sever the major body axes. This capability of whole …

Successful regeneration of missing tissues requires seamless integration of positional
information along the body axes. Planarians, which regenerate from almost any injury, use …

Cullin-RING E3 ubiquitin ligases (CRLs) are a major family of ubiquitin ligases. CRLs are
formed by a scaffold protein (Cullin) that forms a multimeric complex with an E2 ubiquitin …